Zinc in cardiovascular functions and diseases: epidemiology and molecular mechanisms for therapeutic development
T Hara, E Yoshigai, T Ohashi, T Fukada - International journal of …, 2023 - mdpi.com
Zinc is an essential trace element that plays an important physiological role in numerous
cellular processes. Zinc deficiency can result in diverse symptoms, such as impairment of …
cellular processes. Zinc deficiency can result in diverse symptoms, such as impairment of …
Somatic SLC30A1 mutations altering zinc transporter ZnT1 cause aldosterone-producing adenomas and primary aldosteronism
J Rege, S Bandulik, K Nanba, C Kosmann… - Nature Genetics, 2023 - nature.com
Primary aldosteronism (PA) is the most common form of endocrine hypertension and is
characterized by inappropriately elevated aldosterone production via a renin-independent …
characterized by inappropriately elevated aldosterone production via a renin-independent …
The role of Zn2+ in sha** intracellular Ca2+ dynamics in the heart
Increasing evidence suggests that Zn2+ acts as a second messenger capable of
transducing extracellular stimuli into intracellular signaling events. The importance of Zn2+ …
transducing extracellular stimuli into intracellular signaling events. The importance of Zn2+ …
Atrial fibrillation hospitalization is not increased with short‐term elevations in exposure to fine particulate air pollution
TJ Bunch, BD Horne, SJ Asirvatham… - Pacing and clinical …, 2011 - Wiley Online Library
Background: Previous studies have observed that short‐term exposure to elevated
concentrations of particulate matter (PM) air pollution increases risk of acute ischemic heart …
concentrations of particulate matter (PM) air pollution increases risk of acute ischemic heart …
Why is it worth testing the ability of zinc to protect against ischaemia reperfusion injury for human application
Ischaemia (interruption in the blood/oxygen supply) and subsequent damage induced by
reperfusion (restoration of blood/oxygen supply) ultimately leads to cell death, tissue injury …
reperfusion (restoration of blood/oxygen supply) ultimately leads to cell death, tissue injury …
An increase in intercellular crosstalk and electrotonic coupling between cardiomyocytes and nonmyocytes reshapes the electrical conduction in the metabolic heart …
Cardiac conduction abnormalities are disorders in metabolic syndrome (MetS), however,
their mechanisms are unknown. Although ventricular arrhythmia reflects the changes in QT …
their mechanisms are unknown. Although ventricular arrhythmia reflects the changes in QT …
Proarrhythmic atrial calcium cycling in the diseased heart
During the last decades Ca 2+ has been found to play a crucial role in cardiac arrhythmias
associated with heart failure and a number of congenital arrhythmia syndromes. Recent …
associated with heart failure and a number of congenital arrhythmia syndromes. Recent …
Zinc transporter somatic gene mutations cause primary aldosteronism
J Rege, K Nanba, S Bandulik, C Kosmann, AR Blinder… - bioRxiv, 2022 - biorxiv.org
Primary aldosteronism (PA) is the most common form of endocrine hypertension and effects
one in 50 adults. PA is characterized by inappropriately elevated aldosterone production via …
one in 50 adults. PA is characterized by inappropriately elevated aldosterone production via …
The environmental epidemiology of atrial arrhythmogenesis
EA Whitsel, CL Avery - Journal of Epidemiology & Community Health, 2010 - jech.bmj.com
Atrial fibrillation (AF) is the most common cardiac arrhythmia seen in clinical practice, and
makes an important contribution to cardiovascular disease (CVD) and all-cause mortality …
makes an important contribution to cardiovascular disease (CVD) and all-cause mortality …
Oxidative Stress and Labile Zinc in Heart Dysfunction Under Hyperglycemia
B Turan - Oxidative Stress in Heart Diseases, 2019 - Springer
Three major biological roles of zinc (as Zn 2+) in several proteins and enzymes, including
the catalytic, structural and regulatory, brings Zn 2+ to be an important signaling molecule …
the catalytic, structural and regulatory, brings Zn 2+ to be an important signaling molecule …