Curcumin and its derivatives in cancer therapy: Potentiating antitumor activity of cisplatin and reducing side effects
Curcumin is a phytochemical isolated from Curcuma longa with potent tumor‐suppressor
activity, which has shown significant efficacy in pre‐clinical and clinical studies. Curcumin …
activity, which has shown significant efficacy in pre‐clinical and clinical studies. Curcumin …
Repurposing FDA-approved drugs against the toxicity of platinum-based anticancer drugs
Platinum-based anticancer drugs (PADs), mainly cisplatin, carboplatin, and oxaliplatin, are
widely used efficacious long-standing anticancer agents for treating several cancer types …
widely used efficacious long-standing anticancer agents for treating several cancer types …
[PDF][PDF] Ameliorating effect of lycopene and N-acetylcysteine against cisplatin-induced cardiac injury in rats
Cisplatin (CP) is used to treat a wide range of tumors and kills cells (anti-neoplastic drug)
through different mechanisms, including, formation of reactive oxygen species (ROS), DNA …
through different mechanisms, including, formation of reactive oxygen species (ROS), DNA …
Cardioprotective and renoprotective effects of venlafaxine on cisplatin-induced cardiotoxicity and nephrotoxicity in rats
Aim The current work aims to demonstrate the potential defensive function of venlafaxine
(VLF) in cardiotoxicity and nephrotoxicity caused by cisplatin (CP), that could be by …
(VLF) in cardiotoxicity and nephrotoxicity caused by cisplatin (CP), that could be by …
A systematic review of preclinical studies on the taurine role during diabetic nephropathy: focused on anti-oxidative, anti-inflammation, and anti-apoptotic effects
J Ma, Z Yang, S Jia, R Yang - Toxicology Mechanisms and Methods, 2022 - Taylor & Francis
Diabetic nephropathy is one of the most important and growing diseases globally and the
leading cause of cardiovascular mortality in these patients. Taurine is an amino acid that has …
leading cause of cardiovascular mortality in these patients. Taurine is an amino acid that has …
Breast milk mesenchymal stem cells abate cisplatin-induced cardiotoxicity in adult male albino rats via modulating the AMPK pathway
MM Nageeb, SF Saadawy, SH Attia - Scientific Reports, 2022 - nature.com
Myocardial injury influenced by cisplatin (Cis) is a compelling reason to hunt out a treatment
modality to overcome such a threat in cisplatin-treated patients. Breast Milk mesenchymal …
modality to overcome such a threat in cisplatin-treated patients. Breast Milk mesenchymal …
Combination therapy in Mucormycosis: Current evidence from the world literature, a mini review
The emergence of Mucorales infections is an urgent global public health threat rapidly
disseminating during the current COVID-19 pandemic. Invasive mucormycosis carries …
disseminating during the current COVID-19 pandemic. Invasive mucormycosis carries …
Cardiac cachexia: unaddressed aspect in cancer patients
Tumor-derived cachectic factors such as proinflammatory cytokines and neuromodulators
not only affect skeletal muscle but also affect other organs, including the heart, in the form of …
not only affect skeletal muscle but also affect other organs, including the heart, in the form of …
Sinapic acid attenuated cisplatin-induced cardiotoxicity by inhibiting oxidative stress and inflammation with GPX4-mediated NF-kB modulation
The use of cisplatin is severely limited by the risk of develo** cardiovascular
complications. Sinapic acid may reduce cisplatin's side effects. The anti oxidant, anti …
complications. Sinapic acid may reduce cisplatin's side effects. The anti oxidant, anti …
[HTML][HTML] Modulation of miR-205/EGLN2 by rosuvastatin mitigates colistin-induced nephrotoxicity in rats: Involvement of ATF4/CHOP and Nrf2 pathways
Although the beneficial role of microRNA has been investigated thoroughly, the reno-
protective role of microRNA-205 (miR-205) against colistin-induced nephrotoxicity has not …
protective role of microRNA-205 (miR-205) against colistin-induced nephrotoxicity has not …