Preparation and application of pH-responsive drug delivery systems

H Ding, P Tan, S Fu, X Tian, H Zhang, X Ma… - Journal of Controlled …, 2022 - Elsevier
Microenvironment-responsive drug delivery systems (DDSs) can achieve targeted drug
delivery, reduce drug side effects and improve drug efficacies. Among them, pH-responsive …

Multifunctional engineered mesoporous silica/inorganic material hybrid nanoparticles: Theranostic perspectives

NB Fernandes, Y Nayak, S Garg, UY Nayak - Coordination Chemistry …, 2023 - Elsevier
The field of advanced nanotechnology is brimming with a plethora of nanotheranostics
whose combinatorial synergistic applicability in treating malignant tumors is tremendous. But …

Development and evaluation of a pH-responsive Mimosa pudica seed mucilage/β-cyclodextrin-co-poly (methacrylate) hydrogel for controlled drug delivery: In vitro …

T Yasmin, A Mahmood, M Farooq, RM Sarfraz… - International Journal of …, 2024 - Elsevier
In this comprehensive investigation, a novel pH-responsive hydrogel system comprising
mimosa seed mucilage (MSM), β-cyclodextrin (β-CD), and methacrylic acid (MAA) was …

Mesoporous silica nanoparticles as a potential nanoplatform: therapeutic applications and considerations

K Djayanti, P Maharjan, KH Cho, S Jeong… - International Journal of …, 2023 - mdpi.com
With advances in nanotechnology, nanoparticles have come to be regarded as carriers of
therapeutic agents and have been widely studied to overcome various diseases in the …

Inorganic nanoparticle-based treatment approaches for colorectal cancer: recent advancements and challenges

S Narayana, BHJ Gowda, U Hani, SS Shimu… - Journal of …, 2024 - Springer
Colorectal cancer, the third most prevalent cancer globally, contributes significantly to
mortality rates, with over 1.9 million reported cases and nearly 935,000 fatalities annually …

Emerging potential of 5-Fluorouracil-loaded chitosan nanoparticles in cancer therapy

TT Dongsar, TS Dongsar, N Gupta, WH Almalki… - Journal of Drug Delivery …, 2023 - Elsevier
Cancer is among the leading causes of mortality in the globe. Chemotherapy utilizing
various anticancer medicines continues to be the most widely used form of treatment …

[HTML][HTML] An update on mesoporous silica nanoparticle applications in nanomedicine

E Rastegari, YJ Hsiao, WY Lai, YH Lai, TC Yang… - Pharmaceutics, 2021 - mdpi.com
The efficient and safe delivery of therapeutic drugs, proteins, and nucleic acids are essential
for meaningful therapeutic benefits. The field of nanomedicine shows promising implications …

Nanoparticle-based materials in anticancer drug delivery: Current and future prospects

S Ajith, F Almomani, A Elhissi, GA Husseini - Heliyon, 2023 - cell.com
The past decade has witnessed a breakthrough in novel strategies to treat cancer. One of
the most common cancer treatment modalities is chemotherapy which involves …

A new pH-sensitive CS/Zn-MOF@ GO ternary hybrid compound as a biofriendly and implantable platform for prolonged 5-Fluorouracil delivery to human breast cancer …

M Pooresmaeil, EA Asl, H Namazi - Journal of Alloys and Compounds, 2021 - Elsevier
In the current work, we investigated and compared the capability of the monodispersed
chitosan (CS) microspheres, CS coated zinc-based metal-organic framework (CS/Zn-MOF) …

The role of hyaluronic acid in the design and functionalization of nanoparticles for the treatment of colorectal cancer

MC de Paula, SG Carvalho, ALP Silvestre… - Carbohydrate …, 2023 - Elsevier
Despite advances in new approaches for colorectal cancer (CRC) therapy, intravenous
chemotherapy remains one of the main treatment options; however, it has limitations …