[HTML][HTML] Nano-scale delivery systems for siRNA delivery in cancer therapy: New era of gene therapy empowered by nanotechnology

N Ebrahimi, MS Manavi, A Nazari, A Momayezi… - Environmental …, 2023 - Elsevier
RNA interference (RNAi) is a unique treatment approach used to decrease a disease's
excessive gene expression, including cancer. SiRNAs may find and destroy homologous …

siRNA based drug design, quality, delivery and clinical translation

MA Subhan, VP Torchilin - Nanomedicine: Nanotechnology, Biology and …, 2020 - Elsevier
Gene silencing by RNA interference represents a promising therapeutic approach. The
development of carriers, eg, polymers, lipids, peptides, antibodies, aptamers, small …

Biodegradable MnO-based nanoparticles with engineering surface for tumor therapy: simultaneous fenton-like ion delivery and immune activation

Z Sun, Z Wang, T Wang, J Wang, H Zhang, Z Li… - ACS …, 2022 - ACS Publications
Immune checkpoint inhibitors have achieved significant clinical success but are still suffering
from inadequate immune activation. It is worth noting that manganese as a nutritional …

Magnetic/Upconversion Fluorescent NaGdF4:Yb,Er Nanoparticle-Based Dual-Modal Molecular Probes for Imaging Tiny Tumors in Vivo

C Liu, Z Gao, J Zeng, Y Hou, F Fang, Y Li, R Qiao… - ACS …, 2013 - ACS Publications
Detection of early malignant tumors remains clinically difficult; develo** ultrasensitive
imaging agents is therefore highly demanded. Owing to the unusual magnetic and optical …

Engineered redox‐responsive PEG detachment mechanism in PEGylated nano‐graphene oxide for intracellular drug delivery

H Wen, C Dong, H Dong, A Shen, W **a, X Cai, Y Song… - Small, 2012 - Wiley Online Library
In biomedical applications, polyethylene glycol (PEG) functionalization has been a major
approach to modify nanocarriers such as nano‐graphene oxide for particular biological …

[HTML][HTML] Nanoparticle-mediated systemic delivery of siRNA for treatment of cancers and viral infections

MS Draz, BA Fang, P Zhang, Z Hu, S Gu, KC Weng… - Theranostics, 2014 - ncbi.nlm.nih.gov
RNA interference (RNAi) is an endogenous post-transcriptional gene regulatory mechanism,
where non-coding, double-stranded RNA molecules interfere with the expression of certain …

Biomedical nanomaterials for imaging-guided cancer therapy

Y Huang, S He, W Cao, K Cai, XJ Liang - Nanoscale, 2012 - pubs.rsc.org
To date, even though various kinds of nanomaterials have been evaluated over the years in
order to develop effective cancer therapy, there is still significant challenges in the …

Cancer nanomedicine based on polyethylenimine-mediated multifunctional nanosystems

J Li, X Yu, X Shi, M Shen - Progress in Materials Science, 2022 - Elsevier
Owing to the unique structural characteristics and abundant amine groups, polyethylenimine
(PEI) plays a remarkable role in the construction of multifunctional nanosystems for versatile …

A review on the synthesis of manganese oxide nanomaterials and their applications on lithium‐ion batteries

X Liu, C Chen, Y Zhao, B Jia - Journal of Nanomaterials, 2013 - Wiley Online Library
Most recently, manganese oxides nanomaterials, including MnO and MnO2, have attracted
great interest as anode materials in lithium‐ion batteries (LIBs) for their high theoretical …

Stimuli-responsive cancer therapy based on nanoparticles

J Yu, X Chu, Y Hou - Chemical communications, 2014 - pubs.rsc.org
Nanoparticles (NPs) have recently been well investigated for cancer therapy. Among them,
those that are responsive to internal or external stimuli are promising due to their flexibility …