Fungal pathogens are a growing threat to public health. As human immunodeficiency
becomes increasingly common, fungal infections are becoming more prevalent. The use of …

Emergence of resistance is a major factor limiting the efficacy of molecularly targeted
anticancer drugs. Understanding the specific mutations, or other genetic or cellular changes …

Bacterial populations vary in their stress tolerance and population structure depending upon
whether growth occurs in well-mixed or structured environments. We hypothesized that …

Antibiotic resistance represents a growing health crisis that necessitates the immediate
discovery of novel treatment strategies. One such strategy is the identification of collateral …

Heterogeneity in strategies for survival and proliferation among the cells that constitute a
tumour is a driving force behind the evolution of resistance to cancer therapy. The rules …

Background Adaptive therapy aims to tackle cancer drug resistance by leveraging resource
competition between drug-sensitive and resistant cells. Here, we present a theoretical study …