Genomic data are ubiquitous across disciplines, from agriculture to biodiversity, ecology,
evolution and human health. However, these datasets often contain noise or errors and are …

Zokors, an Asiatic group of subterranean rodents, originated in lowlands and colonized high-
elevational zones following the uplift of the Qinghai–Tibet plateau about 3.6 million years …

The cold and hypoxic conditions at high altitude necessitate high metabolic O2 demands to
support thermogenesis while hypoxia reduces O2 availability. Skeletal muscles play key …

High-elevation environments have lower atmospheric oxygen content, reduced
temperatures, and higher levels of UV radiation than found at lower elevations. As such …

As climate change continues, species pushed outside their physiological tolerance limits
must adapt or face extinction. When change is rapid, adaptation will largely harness …

Improved understanding of the genetic basis of adaptation to climate change is necessary
for maintaining global biodiversity moving forward. Studies to date have largely focused on …

Environmental hypoxia challenges female reproductive physiology in placental mammals,
increasing rates of gestational complications. Adaptation to high elevation has limited many …

Our understanding of the limits of animal life is continually revised by scientific exploration of
extreme environments. Here we report the discovery of mummified cadavers of leaf-eared …

A key question in biology concerns the extent to which distributional range limits of species
are determined by intrinsic limits of physiological tolerance. Here, we use common‐garden …

The genus Pristimantis diversified in the tropical Andes mountains and is the most speciose
genus of terrestrial vertebrates. Pristimantis are notable among frogs in that they thrive at …