Mechanisms of oxidative stress in metabolic syndrome

SK Masenga, LS Kabwe, M Chakulya… - International journal of …, 2023 - mdpi.com
Metabolic syndrome is a cluster of conditions associated with the risk of diabetes mellitus
type 2 and cardiovascular diseases (CVDs). Metabolic syndrome is closely related to …

The crucial role and mechanism of insulin resistance in metabolic disease

X Zhao, X An, C Yang, W Sun, H Ji… - Frontiers in endocrinology, 2023 - frontiersin.org
Insulin resistance (IR) plays a crucial role in the development and progression of
metabolism-related diseases such as diabetes, hypertension, tumors, and nonalcoholic fatty …

[HTML][HTML] Pathophysiology of obesity and its associated diseases

X **, T Qiu, L Li, R Yu, X Chen, C Li, CG Proud… - … Pharmaceutica Sinica B, 2023 - Elsevier
The occurrence of obesity has increased across the whole world. Many epidemiological
studies have indicated that obesity strongly contributes to the development of cancer …

[HTML][HTML] Adipose tissue and insulin resistance in obese

B Ahmed, R Sultana, MW Greene - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Currently, obesity has become a global health issue and is referred to as an epidemic.
Dysfunctional obese adipose tissue plays a pivotal role in the development of insulin …

[HTML][HTML] Mechanistic insight into oxidative stress-triggered signaling pathways and type 2 diabetes

A Singh, R Kukreti, L Saso, S Kukreti - Molecules, 2022 - mdpi.com
Oxidative stress (OS) is a metabolic dysfunction mediated by the imbalance between the
biochemical processes leading to elevated production of reactive oxygen species (ROS) …

Pancreatic β-cell dysfunction in type 2 diabetes: Implications of inflammation and oxidative stress

PV Dludla, SE Mabhida, K Ziqubu… - World journal of …, 2023 - pmc.ncbi.nlm.nih.gov
Insulin resistance and pancreatic β-cell dysfunction are major pathological mechanisms
implicated in the development and progression of type 2 diabetes (T2D). Beyond the …

Mecanismos moleculares de la resistencia a la insulina: una actualización

C Gutiérrez-Rodelo, A Roura-Guiberna… - Gaceta médica de …, 2017 - medigraphic.com
Las acciones biológicas de la insulina se inician al activar su receptor de membrana, el cual
desencadena múltiples vías de señalización que median sus acciones biológicas. Debido a …

Propolis: An update on its chemistry and pharmacological applications

R Hossain, C Quispe, RA Khan, ASM Saikat, P Ray… - Chinese medicine, 2022 - Springer
Propolis, a resinous substance produced by honeybees from various plant sources, has
been used for thousands of years in traditional medicine for several purposes all over the …

Obesity cardiomyopathy: evidence, mechanisms, and therapeutic implications

J Ren, NN Wu, S Wang, JR Sowers… - Physiological …, 2021 - journals.physiology.org
The prevalence of heart failure is on the rise and imposes a major health threat, in part, due
to the rapidly increased prevalence of overweight and obesity. To this point …

[HTML][HTML] COVID-19 and metabolic disease: mechanisms and clinical management

C Steenblock, PEH Schwarz, B Ludwig… - The lancet Diabetes & …, 2021 - thelancet.com
Up to 50% of the people who have died from COVID-19 had metabolic and vascular
disorders. Notably, there are many direct links between COVID-19 and the metabolic and …