Selective autophagy is the lysosomal degradation of specific intracellular components
sequestered into autophagosomes, late endosomes, or lysosomes through the activity of …

Selective autophagy relies on soluble or membrane-bound cargo receptors that recognize
cargo and bring about autophagosome formation at the cargo. The cargo-bound receptors …

The clearance of surplus, broken, or dangerous components is key for maintaining cellular
homeostasis. The failure to remove protein aggregates, damaged organelles, or intracellular …

INTRODUCTION Macroautophagy (hereafter autophagy) is an evolutionarily conserved
lysosomal degradation pathway. It ensures cellular homeostasis and health by removing …

In selective autophagy, cytoplasmic components are selected and tagged before being
sequestered into an autophagosome by means of selective autophagy receptors such as …

Autophagy is a highly conserved catabolic process cells use to maintain their homeostasis
by degrading misfolded, damaged and excessive proteins, nonfunctional organelles, foreign …

Mechanisms of selective autophagy of the ER, known as ER-phagy, require molecular
delineation, particularly in vivo. It is unclear how these events control ER proteostasis and …

Over the past two decades, the molecular machinery that underlies autophagic responses
has been characterized with ever increasing precision in multiple model organisms …

The removal of misfolded, ubiquitinated proteins is an essential part of the protein quality
control. The ubiquitin‐proteasome system (UPS) and autophagy are two interconnected …

ATG8 family proteins are evolutionary conserved ubiquitin-like modifiers, which become
attached to the headgroup of the membrane lipid phosphatidylethanolamine in a process …