Recent progress in targeted delivery vectors based on biomimetic nanoparticles

L Chen, W Hong, W Ren, T Xu, Z Qian… - Signal transduction and …, 2021 - nature.com
Over the past decades, great interest has been given to biomimetic nanoparticles (BNPs)
since the rise of targeted drug delivery systems and biomimetic nanotechnology. Biological …

Protein cages: from fundamentals to advanced applications

TGW Edwardson, MD Levasseur, S Tetter… - Chemical …, 2022 - ACS Publications
Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …

Viral nanoparticles for drug delivery, imaging, immunotherapy, and theranostic applications

YH Chung, H Cai, NF Steinmetz - Advanced Drug Delivery Reviews, 2020 - Elsevier
Viral nanoparticles (VNPs) encompass a diverse array of naturally occurring nanomaterials
derived from plant viruses, bacteriophages, and mammalian viruses. The application and …

Protein nanoparticles: promising platforms for drug delivery applications

A Jain, SK Singh, SK Arya, SC Kundu… - … Biomaterials Science & …, 2018 - ACS Publications
The development of drug delivery systems using nanoparticles as carriers for small and
large therapeutic molecules remains a rapidly growing area of research. The advantages of …

Virus‐like particles: Next‐generation nanoparticles for targeted therapeutic delivery

MJ Rohovie, M Nagasawa… - … & translational medicine, 2017 - Wiley Online Library
Most drug therapies distribute the agents throughout the entire body, even though the drugs
are typically only needed at specific tissues. This often limits dosage and causes discomfort …

Bioengineering virus‐like particles as vaccines

LHL Lua, NK Connors, F Sainsbury… - Biotechnology and …, 2014 - Wiley Online Library
Virus‐like particle (VLP) technology seeks to harness the optimally tuned immunostimulatory
properties of natural viruses while omitting the infectious trait. VLPs that assemble from a …

Compartmentalization approaches in soft matter science: from nanoreactor development to organelle mimics

L Schoonen, JCM Van Hest - Advanced Materials, 2016 - Wiley Online Library
Compartmentalization is an essential feature found in living cells to ensure that biological
processes occur without being affected by undesired external influences. Over the years …

Protein cage assembly across multiple length scales

WM Aumiller, M Uchida, T Douglas - Chemical Society Reviews, 2018 - pubs.rsc.org
Within the materials science community, proteins with cage-like architectures are being
developed as versatile nanoscale platforms for use in protein nanotechnology. Much effort …

Encapsulation of an enzyme cascade within the bacteriophage P22 virus-like particle

DP Patterson, B Schwarz, RS Waters… - ACS chemical …, 2014 - ACS Publications
Develo** methods for investigating coupled enzyme systems under conditions that mimic
the cellular environment remains a significant challenge. Here we describe a biomimetic …

Bacteriophages and phage-inspired nanocarriers for targeted delivery of therapeutic cargos

M Karimi, H Mirshekari, SMM Basri, S Bahrami… - Advanced drug delivery …, 2016 - Elsevier
The main goal of drug delivery systems is to target therapeutic cargoes to desired cells and
to ensure their efficient uptake. Recently a number of studies have focused on designing bio …