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Overcoming barriers in photodynamic therapy harnessing nano-formulation strategies
Photodynamic therapy (PDT) has been extensively investigated for decades for tumor
treatment because of its non-invasiveness, spatiotemporal selectivity, lower side-effects, and …
treatment because of its non-invasiveness, spatiotemporal selectivity, lower side-effects, and …
Nanoagent‐promoted mild‐temperature photothermal therapy for cancer treatment
G Gao, X Sun, G Liang - Advanced Functional Materials, 2021 - Wiley Online Library
Photothermal therapy (PTT), which utilizes near‐infrared light‐absorbing agents to ablate
tumor, has emerged as a highly promising anticancer strategy and received intensive …
tumor, has emerged as a highly promising anticancer strategy and received intensive …
Targeting cancer stem cells for reversing therapy resistance: mechanism, signaling, and prospective agents
HM Zhou, JG Zhang, X Zhang, Q Li - Signal transduction and targeted …, 2021 - nature.com
Cancer stem cells (CSCs) show a self-renewal capacity and differentiation potential that
contribute to tumor progression and therapy resistance. However, the underlying processes …
contribute to tumor progression and therapy resistance. However, the underlying processes …
Emerging trends in nanomaterials for antibacterial applications
Around the globe, surges of bacterial diseases are causing serious health threats and
related concerns. Recently, the metal ion release and photodynamic and photothermal …
related concerns. Recently, the metal ion release and photodynamic and photothermal …
Cancer stem cell mimicry for immune evasion and therapeutic resistance
PE Saw, Q Liu, PP Wong, E Song - Cell Stem Cell, 2024 - cell.com
Cancer stem cells (CSCs) are heterogeneous, possess self-renewal attributes, and
orchestrate important crosstalk in tumors. We propose that the CSC state represents" …
orchestrate important crosstalk in tumors. We propose that the CSC state represents" …
Recent advances in calcium‐based anticancer nanomaterials exploiting calcium overload to trigger cell apoptosis
Calcium ion is vital for the regulation of many cellular functions and serves as a second
messenger in the signal transduction pathways. Once the intracellular Ca2+ level exceeds …
messenger in the signal transduction pathways. Once the intracellular Ca2+ level exceeds …
Activating autophagy to potentiate immunogenic chemotherapy and radiation therapy
Autophagy is fundamental to the maintenance of intracellular homeostasis in virtually all
human cells. Accordingly, defective autophagy predisposes healthy cells to undergoing …
human cells. Accordingly, defective autophagy predisposes healthy cells to undergoing …
Repurposing Drugs in Oncology (ReDO)—chloroquine and hydroxychloroquine as anti-cancer agents
C Verbaanderd, H Maes, MB Schaaf… - …, 2017 - pmc.ncbi.nlm.nih.gov
Chloroquine (CQ) and hydroxychloroquine (HCQ) are well-known 4-aminoquinoline
antimalarial agents. Scientific evidence also supports the use of CQ and HCQ in the …
antimalarial agents. Scientific evidence also supports the use of CQ and HCQ in the …
Cell death pathways associated with photodynamic therapy: an update
D Kessel, NL Oleinick - Photochemistry and photobiology, 2018 - Wiley Online Library
Photodynamic therapy (PDT) has the potential to make a significant impact on cancer
treatment. PDT can sensitize malignant tissues to light, leading to a highly selective effect if …
treatment. PDT can sensitize malignant tissues to light, leading to a highly selective effect if …
3-Bromopyruvate-conjugated nanoplatform-induced pro-death autophagy for enhanced photodynamic therapy against hypoxic tumor
Y Deng, P Song, X Chen, Y Huang, L Hong, Q **… - ACS nano, 2020 - ACS Publications
Autophagy triggered by reactive oxygen species (ROS) in photodynamic therapy (PDT)
generally exhibits an anti-apoptotic effect to promote cell survival. Herein, an innovative …
generally exhibits an anti-apoptotic effect to promote cell survival. Herein, an innovative …