Coacervates are condensed liquid-like droplets formed by liquid–liquid phase separation of
molecules through multiple weak associative interactions. In recent years it has emerged …

Supramolecular polymerization can be controlled in space and time by chemical fuels. A
nonassembled monomer is activated by the fuel and subsequently self-assembles into a …

Living and proliferating cells undergo repeated cycles of growth, replication and division, all
orchestrated by complex molecular networks. How a minimal cell cycle emerged and helped …

Coacervates droplets have long been considered as potential protocells to mimic living
cells. However, these droplets lack a membrane and are prone to coalescence, limiting their …

Conspectus As the remit of chemistry expands beyond molecules to systems, new synthetic
targets appear on the horizon. Among these, life represents perhaps the ultimate synthetic …

Metabolism and compartmentalization are two of life's most central elements. Constructing
synthetic assemblies based on prebiotically relevant molecules that combine these …

Phase‐separated compartments can localize (bio) chemical reactions and influence their
kinetics. They are believed to play an important role both in extant life in the form of …

The synthesis of life from non-living matter has captivated and divided scientists for
centuries. This bold goal aims at unraveling the fundamental principles of life and leveraging …

Aqueous two-phase systems (ATPS) are useful in various applications, from purification and
separation of biomolecules to wastewater treatment. While they have great utility on their …

Robust localization of self-reproducing autocatalytic chemistries is a key step in the
realization of heritable and evolvable chemical systems. While autocatalytic chemical …