Animal embryos need to specify different cell types, and the genetic functions that provide
such controls are easy to comprehend since they result in the formation of overtly …

Homeodomain-DNA Recognition Review Page 1 Cell, Vol. 79, 211-223, July 29, 1994, Copyright
0 1994 by Cell Press Homeodomain-DNA Recognition Review Waiter J. Gehring; Yan Giu …

The Drosophila gene eyeless (ey) encodes a transcription factor with both a paired domain
and a homeodomain. It is homologous to the mouse Small eye (Pax-6) gene and to the …

In animals, Hox transcription factors define regional identity in distinct anatomical domains.
How Hox genes encode this specificity is a paradox, because different Hox proteins bind …

Hox genes encode a family of transcriptional regulators that elicit distinct developmental
programmes along the head-to-tail axis of animals. The specific regional functions of …

In D. melanogaster a pulse of the steroid hormone ecdysone triggers the larval-to-adult
metamorphosis, a complex process in which this hormone induces imaginal tissues to …

In recent years researchers have analyzed the expression patterns of the Hox genes in a
multitude of arthropod species, with the hope of understanding the mechanisms at work in …

Thousands of proteins localize to the nucleus; however, it remains unclear which contain
transcriptional effectors. Here, we develop HT-recruit, a pooled assay where protein libraries …

Homeo~ geges idettttfy structures airing the awterior to poster~ axis durisg t~ deeetolns~ of
raost a~ su~ These tes are dusterexl~ to complexe& aKi their wltl~ the c~ uter correkues with …

Regulation of gene expression in eukaryotes is an extremely complex process. In this
review, we break down several critical steps, emphasizing new data and techniques that …