Advances in aptamer-based biomarker discovery

J Huang, X Chen, X Fu, Z Li, Y Huang… - Frontiers in Cell and …, 2021 - frontiersin.org
The discovery and identification of biomarkers promote the rational and fast development of
medical diagnosis and therapeutics. Clinically, the application of ideal biomarkers still is …

Praegnatio perturbatio—impact of endocrine-disrupting chemicals

V Padmanabhan, W Song… - Endocrine …, 2021 - academic.oup.com
The burden of adverse pregnancy outcomes such as preterm birth and low birth weight is
considerable across the world. Several risk factors for adverse pregnancy outcomes have …

Integrated trajectories of the maternal metabolome, proteome, and immunome predict labor onset

IA Stelzer, MS Ghaemi, X Han, K Ando… - Science translational …, 2021 - science.org
Estimating the time of delivery is of high clinical importance because pre-and postterm
deviations are associated with complications for the mother and her offspring. However …

Discovery of sparse, reliable omic biomarkers with Stabl

J Hédou, I Marić, G Bellan, J Einhaus… - Nature …, 2024 - nature.com
Adoption of high-content omic technologies in clinical studies, coupled with computational
methods, has yielded an abundance of candidate biomarkers. However, translating such …

Machine learning applied in maternal and fetal health: a narrative review focused on pregnancy diseases and complications

D Mennickent, A Rodríguez, MC Opazo… - Frontiers in …, 2023 - frontiersin.org
Introduction Machine learning (ML) corresponds to a wide variety of methods that use
mathematics, statistics and computational science to learn from multiple variables …

[HTML][HTML] Microbiome preterm birth DREAM challenge: crowdsourcing machine learning approaches to advance preterm birth research

JL Golob, TT Oskotsky, AS Tang, A Roldan… - Cell Reports …, 2024 - cell.com
Every year, 11% of infants are born preterm with significant health consequences, with the
vaginal microbiome a risk factor for preterm birth. We crowdsource models to predict (1) …

Personalized assessment of cervical length improves prediction of spontaneous preterm birth: a standard and a percentile calculator

DW Gudicha, R Romero, D Kabiri… - American journal of …, 2021 - Elsevier
Background A sonographic short cervix (length< 25 mm during midgestation) is the most
powerful predictor of preterm birth. Current clinical practice assumes that the same cervical …

Predicting preterm birth through vaginal microbiota, cervical length, and WBC using a machine learning model

S Park, J Moon, N Kang, YH Kim, YA You… - Frontiers in …, 2022 - frontiersin.org
An association between the vaginal microbiome and preterm birth has been reported.
However, in practice, it is difficult to predict premature birth using the microbiome because …

Preterm labor and birth: a clinical review

KM Griggs, DA Hrelic, N Williams… - MCN: The American …, 2020 - journals.lww.com
When caring for women experiencing preterm labor and birth, nurses play a significant role
as bedside experts, advocates, patient educators, and key members of the maternity care …

Favorable pregnancy outcomes in women with well-controlled pulmonary arterial hypertension

N Corbach, C Berlier, M Lichtblau, EI Schwarz… - Frontiers in …, 2021 - frontiersin.org
Introduction: Since pregnancy in women with pulmonary arterial hypertension (PAH) is
associated with a high risk of morbidity and mortality, it is recommended that pregnancy …