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Depression and coronary heart disease: 2018 position paper of the ESC working group on coronary pathophysiology and microcirculation
Major depression is a highly prevalent condition, affecting approximately 10% of the
population. 1 It is also a growing global problem, 2 and has been consistently associated …
population. 1 It is also a growing global problem, 2 and has been consistently associated …
Neurotrophic factors and neuroplasticity pathways in the pathophysiology and treatment of depression
Depression is a major health problem with a high prevalence and a heavy socioeconomic
burden in western societies. It is associated with atrophy and impaired functioning of cortico …
burden in western societies. It is associated with atrophy and impaired functioning of cortico …
Glutamate N-methyl-D-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure
BACKGROUND: Despite widely reported clinical and preclinical studies of rapid
antidepressant actions of glutamate N-methyl-D-aspartate (NMDA) receptor antagonists …
antidepressant actions of glutamate N-methyl-D-aspartate (NMDA) receptor antagonists …
Astrocyte pathology in major depressive disorder: insights from human postmortem brain tissue
G Rajkowska, CA Stockmeier - Current drug targets, 2013 - ingentaconnect.com
The present paper reviews astrocyte pathology in major depressive disorder (MDD) and
proposes that reductions in astrocytes and related markers are key features in the pathology …
proposes that reductions in astrocytes and related markers are key features in the pathology …
Structural neuroimaging studies in major depressive disorder: meta-analysis and comparison with bipolar disorder
Context Although differences in clinical characteristics exist between major depressive
disorder (MDD) and bipolar disorder (BD), consistent structural brain abnormalities that …
disorder (MDD) and bipolar disorder (BD), consistent structural brain abnormalities that …
Roles of the medial and lateral orbitofrontal cortex in major depression and its treatment
We describe evidence for dissociable roles of the medial and lateral orbitofrontal cortex
(OFC) in major depressive disorder (MDD) from structure, functional activation, functional …
(OFC) in major depressive disorder (MDD) from structure, functional activation, functional …
Frontocingulate dysfunction in depression: toward biomarkers of treatment response
Increased rostral anterior cingulate cortex (rACC) activity has emerged as a promising
predictor of treatment response in depression, but neither the reliability of this relationship …
predictor of treatment response in depression, but neither the reliability of this relationship …
The neuroprogressive nature of major depressive disorder: pathways to disease evolution and resistance, and therapeutic implications
In some patients with major depressive disorder (MDD), individual illness characteristics
appear consistent with those of a neuroprogressive illness. Features of neuroprogression …
appear consistent with those of a neuroprogressive illness. Features of neuroprogression …
Depression in epilepsy: a systematic review and meta-analysis
Objective: To estimate the prevalence of depression in persons with epilepsy (PWE) and the
strength of association between these 2 conditions. Methods: The MEDLINE (1948–2012) …
strength of association between these 2 conditions. Methods: The MEDLINE (1948–2012) …
Neurobiology of emotion perception II: Implications for major psychiatric disorders
To date, there has been little investigation of the neurobiological basis of emotion
processing abnormalities in psychiatric populations. We have previously discussed two …
processing abnormalities in psychiatric populations. We have previously discussed two …