Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies

H Tian, T Zhang, S Qin, Z Huang, L Zhou, J Shi… - Journal of hematology & …, 2022 - Springer
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …

Advances of nanoparticles as drug delivery systems for disease diagnosis and treatment

R Liu, C Luo, Z Pang, J Zhang, S Ruan, M Wu… - Chinese chemical …, 2023 - Elsevier
Decades have passed since the first nanoparticles-base medicine was approved for human
cancer treatment, and the research and development of nanoparticles for drug delivery are …

[HTML][HTML] Polymer-and lipid-based nanocarriers for ocular drug delivery: current status and future perspectives

H Han, S Li, M Xu, Y Zhong, W Fan, J Xu, T Zhou… - Advanced drug delivery …, 2023 - Elsevier
Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Preparation and application of pH-responsive drug delivery systems

H Ding, P Tan, S Fu, X Tian, H Zhang, X Ma… - Journal of Controlled …, 2022 - Elsevier
Microenvironment-responsive drug delivery systems (DDSs) can achieve targeted drug
delivery, reduce drug side effects and improve drug efficacies. Among them, pH-responsive …

Current advance of nanotechnology in diagnosis and treatment for malignant tumors

B Wang, S Hu, Y Teng, J Chen, H Wang, Y Xu… - … and Targeted Therapy, 2024 - nature.com
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

Rational design in photopharmacology with molecular photoswitches

P Kobauri, FJ Dekker, W Szymanski… - Angewandte Chemie …, 2023 - Wiley Online Library
Photopharmacology is an attractive approach for achieving targeted drug action with the use
of light. In photopharmacology, molecular photoswitches are introduced into the structure of …

[HTML][HTML] Advanced application of stimuli-responsive drug delivery system for inflammatory arthritis treatment

M Zhang, W Hu, C Cai, Y Wu, J Li, S Dong - Materials Today Bio, 2022 - Elsevier
Inflammatory arthritis is a major cause of disability in the elderly. This condition causes joint
pain, loss of function, and deterioration of quality of life, mainly due to osteoarthritis (OA) and …

Nanoparticle drug delivery systems and their applications as targeted therapies for triple negative breast cancer

X Kong, Y Qi, X Wang, R Jiang, J Wang, Y Fang… - Progress in materials …, 2023 - Elsevier
The therapeutic effect of highly malignant triple negative breast cancer (TNBC) is negatively
affected by the formation of tumor cell resistant clone and the severe toxicity of …

Stimuli‐Responsive AIEgens

J Zhang, B He, Y Hu, P Alam, H Zhang… - Advanced …, 2021 - Wiley Online Library
The unique advantages and the exciting application prospects of AIEgens have triggered
booming developments in this area in recent years. Among them, stimuli‐responsive …