Obesity I: Overview and molecular and biochemical mechanisms
Obesity is a chronic, relapsing condition characterized by excess body fat. Its prevalence
has increased globally since the 1970s, and the number of obese and overweight people is …
has increased globally since the 1970s, and the number of obese and overweight people is …
Exosome-derived microRNAs of human milk and their effects on infant health and development
BC Melnik, W Stremmel, R Weiskirchen, SM John… - Biomolecules, 2021 - mdpi.com
Multiple biologically active components of human milk support infant growth, health and
development. Milk provides a wide spectrum of mammary epithelial cell-derived …
development. Milk provides a wide spectrum of mammary epithelial cell-derived …
SCFAs strongly stimulate PYY production in human enteroendocrine cells
P Larraufie, C Martin-Gallausiaux, N Lapaque, J Dore… - Scientific reports, 2018 - nature.com
Abstract Peptide-YY (PYY) and Glucagon-Like Peptide-1 (GLP-1) play important roles in the
regulation of food intake and insulin secretion, and are of translational interest in the field of …
regulation of food intake and insulin secretion, and are of translational interest in the field of …
Western diet: implications for brain function and behavior
I López-Taboada, H González-Pardo… - Frontiers in …, 2020 - frontiersin.org
The Western diet (WD) pattern characterized by high daily intake of saturated fats and
refined carbohydrates often leads to obesity and overweight, and it has been linked to …
refined carbohydrates often leads to obesity and overweight, and it has been linked to …
[HTML][HTML] Fermented foods: Harnessing their potential to modulate the microbiota-gut-brain axis for mental health
Over the past two decades, whole food supplementation strategies have been leveraged to
target mental health. In addition, there has been increasing attention on the ability of gut …
target mental health. In addition, there has been increasing attention on the ability of gut …
Gut microbiota link dietary fiber intake and short-chain fatty acid metabolism with eating behavior
The gut microbiome has been speculated to modulate feeding behavior through multiple
factors, including short-chain fatty acids (SCFA). Evidence on this relationship in humans is …
factors, including short-chain fatty acids (SCFA). Evidence on this relationship in humans is …
The role of dietary fibers in regulating appetite, an overview of mechanisms and weight consequences
M Akhlaghi - Critical Reviews in Food Science and Nutrition, 2024 - Taylor & Francis
Dietary fibers prevent obesity through reduction of hunger and prolongation of satiety. A
number of mechanical and endocrine signals from gastrointestinal tract are stimulated by …
number of mechanical and endocrine signals from gastrointestinal tract are stimulated by …
Integrative hedonic and homeostatic food intake regulation by the central nervous system: insights from neuroimaging
Food intake regulation in humans is a complex process controlled by the dynamic
interaction of homeostatic and hedonic systems. Homeostatic regulation is controlled by …
interaction of homeostatic and hedonic systems. Homeostatic regulation is controlled by …
Intranasal insulin
M Hallschmid - Journal of neuroendocrinology, 2021 - Wiley Online Library
The intranasal (IN) route enables the delivery of insulin to the central nervous system in the
relative absence of systemic uptake and related peripheral side effects. Intranasally …
relative absence of systemic uptake and related peripheral side effects. Intranasally …
Treatment of acquired hypothalamic obesity: now and the future
P Dimitri - Frontiers in Endocrinology, 2022 - frontiersin.org
The hypothalamus is the centre of neuroendocrine regulation of energy homeostasis and
appetite. Maldevelopment of, or damage to, the key hypothalamic nuclei disrupts the …
appetite. Maldevelopment of, or damage to, the key hypothalamic nuclei disrupts the …