Distinguishing features of current COVID-19 vaccines: knowns and unknowns of antigen presentation and modes of action
FX Heinz, K Stiasny - npj Vaccines, 2021 - nature.com
COVID-19 vaccines were developed with an unprecedented pace since the beginning of the
pandemic. Several of them have reached market authorization and mass production …
pandemic. Several of them have reached market authorization and mass production …
Antibody-mediated neutralization of SARS-CoV-2
Neutralizing antibodies can block infection, clear pathogens, and are essential to provide
long-term immunity. Since the onset of the pandemic, SARS-CoV-2 neutralizing antibodies …
long-term immunity. Since the onset of the pandemic, SARS-CoV-2 neutralizing antibodies …
LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants
K Westendorf, S Žentelis, L Wang, D Foster… - Cell reports, 2022 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal
antibodies (mAbs) can reduce the risk of hospitalization from coronavirus disease 2019 …
antibodies (mAbs) can reduce the risk of hospitalization from coronavirus disease 2019 …
In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains
Rapidly emerging SARS-CoV-2 variants jeopardize antibody-based countermeasures.
Although cell culture experiments have demonstrated a loss of potency of several anti-spike …
Although cell culture experiments have demonstrated a loss of potency of several anti-spike …
Hybrid immunity improves B cells and antibodies against SARS-CoV-2 variants
The emergence of SARS-CoV-2 variants is jeopardizing the effectiveness of current
vaccines and limiting the application of monoclonal antibody-based therapy for COVID-19 …
vaccines and limiting the application of monoclonal antibody-based therapy for COVID-19 …
SARS-CoV-2 escape from a highly neutralizing COVID-19 convalescent plasma
E Andreano, G Piccini, D Licastro… - Proceedings of the …, 2021 - National Acad Sciences
To investigate the evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) in the immune population, we coincupi bated the authentic virus with a highly neutralizing …
2) in the immune population, we coincupi bated the authentic virus with a highly neutralizing …
A nanomaterial targeting the spike protein captures SARS-CoV-2 variants and promotes viral elimination
The global emergency caused by the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) pandemic can only be solved with effective and widespread preventive and …
(SARS-CoV-2) pandemic can only be solved with effective and widespread preventive and …
Comparison of the immunogenicity of BNT162b2 and CoronaVac COVID‐19 vaccines in Hong Kong
CKP Mok, CA Cohen, SMS Cheng, C Chen… - …, 2022 - Wiley Online Library
Background and objective Few head‐to‐head evaluations of immune responses to different
vaccines have been reported. Methods Surrogate virus neutralization test (sVNT) antibody …
vaccines have been reported. Methods Surrogate virus neutralization test (sVNT) antibody …
SARS-CoV-2 Omicron-neutralizing memory B cells are elicited by two doses of BNT162b2 mRNA vaccine
R Kotaki, Y Adachi, S Moriyama, T Onodera… - Science …, 2022 - science.org
Multiple SARS-CoV-2 variants have mutations in the spike receptor binding domain (RBD)
with potential to evade neutralizing antibody. In particular, the Beta and Omicron variants …
with potential to evade neutralizing antibody. In particular, the Beta and Omicron variants …
Temporal maturation of neutralizing antibodies in COVID-19 convalescent individuals improves potency and breadth to circulating SARS-CoV-2 variants
S Moriyama, Y Adachi, T Sato, K Tonouchi, L Sun… - Immunity, 2021 - cell.com
Antibody titers against SARS-CoV-2 slowly wane over time. Here, we examined how time
affects antibody potency. To assess the impact of antibody maturation on durable …
affects antibody potency. To assess the impact of antibody maturation on durable …