Next-generation, personalised, model-based critical care medicine: a state-of-the art review of in silico virtual patient models, methods, and cohorts, and how to …
Critical care, like many healthcare areas, is under a dual assault from significantly
increasing demographic and economic pressures. Intensive care unit (ICU) patients are …
increasing demographic and economic pressures. Intensive care unit (ICU) patients are …
Glycemic control in the intensive care unit: a control systems perspective
Computers and automation have revolutionised quality and productivity in many industries,
but not in medicine. Healthcare costs are thus growing beyond the ability of society to pay for …
but not in medicine. Healthcare costs are thus growing beyond the ability of society to pay for …
Untangling glycaemia and mortality in critical care
Background Hyperglycaemia is associated with adverse outcomes in the intensive care unit,
and initial studies suggested outcome benefits of glycaemic control (GC). However …
and initial studies suggested outcome benefits of glycaemic control (GC). However …
Hyperglycemia in medically critically ill patients: risk factors and clinical outcomes
CD Becker, RL Sabang, MFN Cordeiro… - The American journal of …, 2020 - Elsevier
Background We aimed to robustly categorize glycemic control in our medical intensive care
unit (ICU) as either acceptable or suboptimal based on time-weighted daily blood glucose …
unit (ICU) as either acceptable or suboptimal based on time-weighted daily blood glucose …
Physiological modeling, tight glycemic control, and the ICU clinician: what are models and how can they affect practice?
Critically ill patients are highly variable in their response to care and treatment. This
variability and the search for improved outcomes have led to a significant increase in the use …
variability and the search for improved outcomes have led to a significant increase in the use …
[HTML][HTML] Relationship between glucocorticoids and insulin resistance in healthy individuals
PZ Zhou, YM Zhu, GH Zou, YX Sun, XL **u… - … medical journal of …, 2016 - ncbi.nlm.nih.gov
Relationship Between Glucocorticoids and Insulin Resistance in Healthy Individuals - PMC Back
to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage …
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A controlled study of the effectiveness of an adaptive closed-loop algorithm to minimize corticosteroid-induced stress hyperglycemia in type 1 diabetes
JE Youssef, JR Castle, DL Branigan, RG Massoud… - 2011 - journals.sagepub.com
To be effective in type 1 diabetes, algorithms must be able to limit hyperglycemic excursions
resulting from medical and emotional stress. We tested an algorithm that estimates insulin …
resulting from medical and emotional stress. We tested an algorithm that estimates insulin …
Virtual patients and virtual cohorts: a new way to think about the design and implementation of personalized ICU treatments
Intensive care unit (ICU) patients exhibit complex and highly variable behavior, making them
very difficult to manage efficiently and safely. More pragmatically, the cost of intensive care …
very difficult to manage efficiently and safely. More pragmatically, the cost of intensive care …
Impact of sensor and measurement timing errors on model-based insulin sensitivity
CG Pretty, M Signal, L Fisk, S Penning… - Computer Methods and …, 2014 - Elsevier
A model-based insulin sensitivity parameter (SI) is often used in glucose–insulin system
models to define the glycaemic response to insulin. As a parameter identified from clinical …
models to define the glycaemic response to insulin. As a parameter identified from clinical …
Nutrition delivery, workload and performance in a model-based ICU glycaemic control system
Abstract Background and Objective Hyperglycaemia is commonplace in the adult intensive
care unit (ICU), and has been associated with increased morbidity and mortality. Effective …
care unit (ICU), and has been associated with increased morbidity and mortality. Effective …