Systematic review of the genetics of sudden unexpected death in epilepsy: potential overlap with sudden cardiac death and arrhythmia‐related genes

CAA Chahal, MN Salloum, F Alahdab… - Journal of the …, 2020 - Am Heart Assoc
Background Sudden unexpected death in epilepsy (SUDEP) is the leading cause of
epilepsy‐related death. SUDEP shares many features with sudden cardiac death and …

An official ATS clinical policy statement: congenital central hypoventilation syndrome: genetic basis, diagnosis, and management

DE Weese-Mayer, EM Berry-Kravis… - American journal of …, 2010 - atsjournals.org
Background: Congenital central hypoventilation syndrome (CCHS) is characterized by
alveolar hypoventilation and autonomic dysregulation. Purpose:(1) To demonstrate the …

The genetics of congenital central hypoventilation syndrome: clinical implications

J Bishara, TG Keens, IA Perez - The Application of Clinical …, 2018 - Taylor & Francis
Congenital central hypoventilation syndrome (CCHS) is a rare genetic disorder of the
autonomic nervous system (ANS) and respiratory control. This disorder, formerly referred to …

Idiopathic congenital central hypoventilation syndrome: analysis of genes pertinent to early autonomic nervous system embryologic development and identification of …

DE Weese‐Mayer, EM Berry‐Kravis… - American journal of …, 2003 - Wiley Online Library
Idiopathic congenital central hypoventilation syndrome (CCHS) has been linked to
autonomic nervous system dysregulation and/or dysfunction (ANSD) since it was first …

Epidemiologic survey of 196 patients with congenital central hypoventilation syndrome

M Vanderlaan, CR Holbrook, M Wang… - Pediatric …, 2004 - Wiley Online Library
This study examined the cross‐sectional medical and social characteristics of children
diagnosed with congenital central hypoventilation syndrome (CCHS). A detailed …

Transitional care and clinical management of adolescents, young adults, and suspected new adult patients with congenital central hypoventilation syndrome

SM Slattery, IA Perez, I Ceccherini, ML Chen… - Clinical Autonomic …, 2023 - Springer
Purpose With contemporaneous advances in congenital central hypoventilation syndrome
(CCHS), recognition, confirmatory diagnostics with PHOX2B genetic testing, and …

Heart rate variability in congenital central hypoventilation syndrome: relationships with hypertension and sinus pauses

B Dudoignon, I Denjoy, M Patout, B Matrot… - Pediatric …, 2023 - nature.com
Background Autonomic nervous system (ANS) dysregulation has been described in
congenital central hypoventilation syndrome (CCHS). The objectives were to describe heart …

Congenital central hypoventilation syndrome: a bedside-to-bench success story for advancing early diagnosis and treatment and improved survival and quality of life

DE Weese-Mayer, CM Rand, A Zhou, MS Carroll… - Pediatric …, 2017 - nature.com
Abstract The “bedside-to-bench” Congenital Central Hypoventilation Syndrome (CCHS)
research journey has led to increased phenotypic-genotypic knowledge regarding …

Congenital central hypoventilation syndrome: diagnosis and management

MA Maloney, SS Kun, TG Keens… - Expert Review of …, 2018 - Taylor & Francis
Introduction: Congenital central hypoventilation syndrome (CCHS) is a rare disorder defined
by a failure in autonomic control of breathing secondary to mutations of the PHOX2B gene …

Pediatric home mechanical ventilation: a Canadian Thoracic Society clinical practice guideline executive summary

R Amin, I MacLusky, D Zielinski… - Canadian Journal of …, 2017 - Taylor & Francis
Over the last 30 to 40 years, improvements in technology, as well as changing clinical
practice regarding the appropriateness of long-term ventilation in patients with “non-curable” …