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Bipolar disorder diagnosis: challenges and future directions
ML Phillips, DJ Kupfer - The Lancet, 2013 - thelancet.com
Bipolar disorder refers to a group of affective disorders, which together are characterised by
depressive and manic or hypomanic episodes. These disorders include: bipolar disorder …
depressive and manic or hypomanic episodes. These disorders include: bipolar disorder …
A critical appraisal of neuroimaging studies of bipolar disorder: toward a new conceptualization of underlying neural circuitry and a road map for future research
ML Phillips, HA Swartz - American Journal of Psychiatry, 2014 - psychiatryonline.org
Objective In this critical review, the authors appraise neuroimaging findings in bipolar
disorder in emotion-processing, emotion-regulation, and reward-processing neural circuitry …
disorder in emotion-processing, emotion-regulation, and reward-processing neural circuitry …
Differentiating between bipolar and unipolar depression in functional and structural MRI studies
Distinguishing depression in bipolar disorder (BD) from unipolar depression (UD) solely
based on clinical clues is difficult, which has led to the exploration of promising neural …
based on clinical clues is difficult, which has led to the exploration of promising neural …
Integrated neurobiology of bipolar disorder
V Maletic, C Raison - Frontiers in psychiatry, 2014 - frontiersin.org
From a neurobiological perspective there is no such thing as bipolar disorder. Rather, it is
almost certainly the case that many somewhat similar, but subtly different, pathological …
almost certainly the case that many somewhat similar, but subtly different, pathological …
Distinguishing between unipolar depression and bipolar depression: current and future clinical and neuroimaging perspectives
JRC de Almeida, ML Phillips - Biological psychiatry, 2013 - Elsevier
Differentiating bipolar disorder (BD) from recurrent unipolar depression (UD) is a major
clinical challenge. Main reasons for this include the higher prevalence of depressive relative …
clinical challenge. Main reasons for this include the higher prevalence of depressive relative …
Biomarkers in bipolar disorder: a positional paper from the International Society for Bipolar Disorders Biomarkers Task Force
Although the etiology of bipolar disorder remains uncertain, multiple studies examining
neuroimaging, peripheral markers and genetics have provided important insights into the …
neuroimaging, peripheral markers and genetics have provided important insights into the …
Systematic review and voxel-based meta-analysis of diffusion tensor imaging studies in bipolar disorder
Background Diffusion tensor imaging (DTI) studies have shown changes in the
microstructure of white matter in bipolar disorder. Studies suggest both localised …
microstructure of white matter in bipolar disorder. Studies suggest both localised …
[HTML][HTML] A review of white matter microstructure alterations of pathways of the reward circuit in depression
Background Depressed mood, anhedonia, psychomotor retardation and alterations of
circadian rhythm are core features of the depressive syndrome. Its neural correlates can be …
circadian rhythm are core features of the depressive syndrome. Its neural correlates can be …
Diffusion tensor imaging white matter endophenotypes in patients with schizophrenia or psychotic bipolar disorder and their relatives
P Skudlarski, DJ Schretlen, GK Thaker… - American Journal of …, 2013 - psychiatryonline.org
Objective Both schizophrenia and bipolar disorder are hypothesized to involve disordered
brain connectivity. Prior studies show low white matter integrity, measured with diffusion …
brain connectivity. Prior studies show low white matter integrity, measured with diffusion …
Elevated serum measures of lipid peroxidation and abnormal prefrontal white matter in euthymic bipolar adults: toward peripheral biomarkers of bipolar disorder
Diffusion tensor imaging (DTI) studies consistently reported abnormalities in fractional
anisotropy (FA) and radial diffusivity (RD), measures of the integrity of white matter (WM), in …
anisotropy (FA) and radial diffusivity (RD), measures of the integrity of white matter (WM), in …