Bipolar disorder diagnosis: challenges and future directions

ML Phillips, DJ Kupfer - The Lancet, 2013 - thelancet.com
Bipolar disorder refers to a group of affective disorders, which together are characterised by
depressive and manic or hypomanic episodes. These disorders include: bipolar disorder …

A critical appraisal of neuroimaging studies of bipolar disorder: toward a new conceptualization of underlying neural circuitry and a road map for future research

ML Phillips, HA Swartz - American Journal of Psychiatry, 2014 - psychiatryonline.org
Objective In this critical review, the authors appraise neuroimaging findings in bipolar
disorder in emotion-processing, emotion-regulation, and reward-processing neural circuitry …

Differentiating between bipolar and unipolar depression in functional and structural MRI studies

KM Han, D De Berardis, M Fornaro, YK Kim - Progress in Neuro …, 2019 - Elsevier
Distinguishing depression in bipolar disorder (BD) from unipolar depression (UD) solely
based on clinical clues is difficult, which has led to the exploration of promising neural …

Integrated neurobiology of bipolar disorder

V Maletic, C Raison - Frontiers in psychiatry, 2014 - frontiersin.org
From a neurobiological perspective there is no such thing as bipolar disorder. Rather, it is
almost certainly the case that many somewhat similar, but subtly different, pathological …

Distinguishing between unipolar depression and bipolar depression: current and future clinical and neuroimaging perspectives

JRC de Almeida, ML Phillips - Biological psychiatry, 2013 - Elsevier
Differentiating bipolar disorder (BD) from recurrent unipolar depression (UD) is a major
clinical challenge. Main reasons for this include the higher prevalence of depressive relative …

Biomarkers in bipolar disorder: a positional paper from the International Society for Bipolar Disorders Biomarkers Task Force

BN Frey, AC Andreazza, J Houenou… - Australian & New …, 2013 - journals.sagepub.com
Although the etiology of bipolar disorder remains uncertain, multiple studies examining
neuroimaging, peripheral markers and genetics have provided important insights into the …

Systematic review and voxel-based meta-analysis of diffusion tensor imaging studies in bipolar disorder

G Nortje, DJ Stein, J Radua, D Mataix-Cols… - Journal of affective …, 2013 - Elsevier
Background Diffusion tensor imaging (DTI) studies have shown changes in the
microstructure of white matter in bipolar disorder. Studies suggest both localised …

[HTML][HTML] A review of white matter microstructure alterations of pathways of the reward circuit in depression

T Bracht, D Linden, P Keedwell - Journal of affective disorders, 2015 - Elsevier
Background Depressed mood, anhedonia, psychomotor retardation and alterations of
circadian rhythm are core features of the depressive syndrome. Its neural correlates can be …

Diffusion tensor imaging white matter endophenotypes in patients with schizophrenia or psychotic bipolar disorder and their relatives

P Skudlarski, DJ Schretlen, GK Thaker… - American Journal of …, 2013 - psychiatryonline.org
Objective Both schizophrenia and bipolar disorder are hypothesized to involve disordered
brain connectivity. Prior studies show low white matter integrity, measured with diffusion …

Elevated serum measures of lipid peroxidation and abnormal prefrontal white matter in euthymic bipolar adults: toward peripheral biomarkers of bipolar disorder

A Versace, AC Andreazza, LT Young, JC Fournier… - Molecular …, 2014 - nature.com
Diffusion tensor imaging (DTI) studies consistently reported abnormalities in fractional
anisotropy (FA) and radial diffusivity (RD), measures of the integrity of white matter (WM), in …