Computational models in cardiology

SA Niederer, J Lumens, NA Trayanova - Nature reviews cardiology, 2019 - nature.com
The treatment of individual patients in cardiology practice increasingly relies on advanced
imaging, genetic screening and devices. As the amount of imaging and other diagnostic …

Computational modeling of cardiac electrophysiology and arrhythmogenesis: toward clinical translation

NA Trayanova, A Lyon, J Shade… - Physiological …, 2024 - journals.physiology.org
The complexity of cardiac electrophysiology, involving dynamic changes in numerous
components across multiple spatial (from ion channel to organ) and temporal (from …

Personalized cardiac computational models: from clinical data to simulation of infarct-related ventricular tachycardia

A Lopez-Perez, R Sebastian, M Izquierdo… - Frontiers in …, 2019 - frontiersin.org
In the chronic stage of myocardial infarction, a significant number of patients develop life-
threatening ventricular tachycardias (VT) due to the arrhythmogenic nature of the remodeled …

European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) …

JC Nielsen, YJ Lin, MJ de Oliveira Figueiredo… - Ep …, 2020 - academic.oup.com
Patients with cardiac diseases or conditions with high risk of develo** cardiac diseases
undergo risk assessment by cardiologists, primary care physicians, and scientists based on …

Modeling the electrophysiological properties of the infarct border zone

C Mendonca Costa, G Plank, CA Rinaldi… - Frontiers in …, 2018 - frontiersin.org
Ventricular arrhythmias (VA) in patients with myocardial infarction (MI) are thought to be
associated with structural and electrophysiological remodeling within the infarct border zone …

Up digital and personal: How heart digital twins can transform heart patient care

NA Trayanova, A Prakosa - Heart Rhythm, 2024 - Elsevier
Precision medicine is the vision of health care where therapy is tailored to each patient. As
part of this vision, digital twinning technology promises to deliver a digital representation of …

From evidence-based medicine to digital twin technology for predicting ventricular tachycardia in ischaemic cardiomyopathy

AGW de Lepper, CMA Buck… - Journal of the …, 2022 - royalsocietypublishing.org
Survivors of myocardial infarction are at risk of life-threatening ventricular tachycardias (VTs)
later in their lives. Current guidelines for implantable cardioverter defibrillators (ICDs) …

[PDF][PDF] 25 years of basic and translational science in EP Europace: novel insights into arrhythmia mechanisms and therapeutic strategies

CA Remme, J Heijman, AM Gomez, A Zaza… - Europace, 2023 - academic.oup.com
In the last 25 years, EP Europace has published more than 300 basic and translational
science articles covering different arrhythmia types (ranging from atrial fibrillation to …

[PDF][PDF] TF-Unet: An automatic cardiac MRI image segmentation method

Z Fu, J Zhang, R Luo, Y Sun, D Deng, L **a - Math. Biosci. Eng, 2022 - aimspress.com
Personalized heart models are widely used to study the mechanisms of cardiac arrhythmias
and have been used to guide clinical ablation of different types of arrhythmias in recent …

[HTML][HTML] Multipatch isogeometric analysis for electrophysiology: simulation in a human heart

M Bucelli, M Salvador, A Quarteroni - Computer Methods in Applied …, 2021 - Elsevier
In the framework of cardiac electrophysiology for the human heart, we apply multipatch
NURBS-based Isogeometric Analysis for the space discretization of the Monodomain model …