Multidrug-Resistant Candida: Epidemiology, Molecular Mechanisms, and Treatment

MC Arendrup, TF Patterson - The Journal of infectious diseases, 2017 - academic.oup.com
Invasive Candida infections remain an important cause of morbidity and mortality, especially
in hospitalized and immunocompromised or critically ill patients. A limited number of …

Clinical, cellular, and molecular factors that contribute to antifungal drug resistance

TC White, KA Marr, RA Bowden - Clinical microbiology reviews, 1998 - Am Soc Microbiol
In the past decade, the frequency of diagnosed fungal infections has risen sharply due to
several factors, including the increase in the number of immunosuppressed patients …

Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences

D Sanglard, FC Odds - The Lancet infectious diseases, 2002 - thelancet.com
Candida albicans and related species pathogenic for man become resistant to antifungal
agents, in particular triazole compounds, by expression of efflux pumps that reduce drug …

Rare and Emerging Opportunistic Fungal Pathogens: Concern for Resistance beyond Candida albicans and Aspergillus fumigatus

MA Pfaller, DJ Diekema - Journal of clinical microbiology, 2004 - Am Soc Microbiol
The frequency of invasive mycoses due to opportunistic fungal pathogens has increased
significantly over the past two decades (35, 74, 83, 88, 89, 101, 106). This increase in …

Nipah virus infection in bats (order Chiroptera) in peninsular Malaysia.

JM Yob, H Field, AM Rashdi, C Morrissy… - Emerging infectious …, 2001 - ncbi.nlm.nih.gov
Nipah virus, family Paramyxoviridae, caused disease in pigs and humans in peninsular
Malaysia in 1998-99. Because Nipah virus appears closely related to Hendra virus, wildlife …

Antifungal drug resistance

J Loeffler, DA Stevens - Clinical infectious diseases, 2003 - academic.oup.com
The increasing incidence of invasive fungal infections is the result of many factors, including
an increasing number of patients with severe immunosuppression. Although new drugs …

Laboratory diagnosis of invasive candidiasis

NB Ellepola Arjuna, J Morrison Christine - Journal of microbiology, 2005 - koreascience.kr
Invasive candidiasis is associated with high morbidity and mortality. Clinical diagnosis is
complicated by a lack of specific clinical signs and symptoms of disease. Laboratory …

The ins and outs of DNA fingerprinting the infectious fungi

DR Soll - Clinical Microbiology Reviews, 2000 - Am Soc Microbiol
SUMMARY DNA fingerprinting methods have evolved as major tools in fungal
epidemiology. However, no single method has emerged as the method of choice, and some …

Yeast identification—past, present, and future methods

DH Pincus, S Orenga, S Chatellier - Medical mycology, 2007 - academic.oup.com
The focus of this review is the evolution of biochemical phenotypic yeast identification
methods with emphasis on conventional approaches, rapid screening tests, chromogenic …

Comparison of the epidemiology, drug resistance mechanisms, and virulence of Candida dubliniensis and Candida albicans

DJ Sullivan, GP Moran, E Pinjon… - FEMS yeast …, 2004 - academic.oup.com
Candida dubliniensis is a pathogenic yeast species that was first identified as a distinct
taxon in 1995. Epidemiological studies have shown that C. dubliniensis is prevalent …