Down Syndrome (DS) is the most common genetic form of intellectual disability that leads in
the majority of cases to development of early-onset Alzheimer-like dementia (AD). The …

Down syndrome (DS) is one of the most common genetic causes of intellectual disability
characterized by multiple pathological phenotypes, among which neurodegeneration is a …

Proteomics has a wide range of applications, including determination of differences in the
proteome in terms of expression and post‐translational protein modifications. Redox …

Epigallocatechin gallate (EGCG) is an inhibitor of DYRK1A, a serine/threonine kinase
considered to be a major contributor of cognitive dysfunctions in Down syndrome (DS). Two …

Down syndrome (DS) is the most common genetic disorder leading to developmental
disability. The phenotypes associated with DS are complex and vary between affected …

Prenatal screening for Down syndrome (DS) is based on both noninvasive and invasive
methods. Noninvasive, cell-free fetal DNA genetic tests are expensive, whereas biochemical …

BACKGROUND Down syndrome (DS) is one of the most common chromosomal aneuploidy
diseases. Prenatal screening and diagnostic tests can aid the early diagnosis, appropriate …

Down syndrome (DS) is one of the most common chromosomal abnormalities affecting
about 1 of every 700 fetuses. Current screening strategies have detection rates of 90–95 …

As the chromosomal examination of foetal cells for the prenatal diagnosis of Down's
syndrome (DS) carries a risk of inducing miscarriage, serum screening tests are commonly …

It is essential for nurses to recognize the impact that genetics and genomics have on their
practice as both genetic science and the nursing discipline move forward in the twenty-first …