Therapeutic Effects of Alisma orientale and its Active Constituents on Cardiovascular Disease and Obesity

Y Wu, X Wang, L Yang, S Kang, G Yan… - The American Journal …, 2023 - World Scientific
The treatment of cardiovascular diseases and obesity, two diseases posing a major risk to
human health, has been plagued by the scarcity of potent and effective medication with …

Advances in molecular regulation of prostate cancer cells by top natural products of Malaysia

JM Prieto, MMM Hanafi - Current Issues in Molecular Biology, 2023 - mdpi.com
Prostate cancer (PCa) remains both a global health burden and a scientific challenge. We
present a review of the molecular targets driving current drug discovery to fight this disease …

[HTML][HTML] PSMA-targeted combination brusatol and docetaxel nanotherapeutics for the treatment of prostate cancer

TA Adekiya, T Hudson, O Bakare, EE Ameyaw… - Biomedicine & …, 2024 - Elsevier
Active targeting to cancer involves exploiting specific interactions between receptors on the
surface of cancer cells and targeting moieties conjugated to the surface of vectors such that …

The potential of PSMA as a vascular target in TNBC

A Heesch, L Ortmanns, J Maurer, E Stickeler… - Cells, 2023 - mdpi.com
Recent studies proving prostate-specific membrane antigen (PSMA) expression on triple-
negative breast cancer (TNBC) cells and adjacent endothelial cells suggest PSMA as a …

Membrane-derived particles shed by PSMA-positive cells function as pro-angiogenic stimuli in tumors

CML Machado, M Skubal, K Haedicke, FP Silva… - Journal of Controlled …, 2023 - Elsevier
Cell membrane-derived particles (Mp) are rounded membrane-enclosed particles that are
shed from tumor cells. Mp are formed from tumor membranes and are capable of tumor …

Secreted phosphoprotein 1 promotes angiogenesis of glioblastoma through upregulating PSMA expression via transcription factor HIF1α: SPP1 promotes …

W Tu, H Zheng, L Li, C Zhou, M Feng… - Acta Biochimica et …, 2022 - pmc.ncbi.nlm.nih.gov
Glioblastoma multiforme (GBM) is a highly vascularized malignant brain tumor. Our previous
study showed that prostate-specific membrane antigen (PSMA) promotes angiogenesis of …

Comparison of Nuclear Medicine Therapeutics Targeting PSMA among Alpha-Emitting Nuclides

K Kaneda-Nakashima, Y Shirakami… - International Journal of …, 2024 - mdpi.com
Currently, targeted alpha therapy (TAT) is a new therapy involving the administration of a
therapeutic drug that combines a substance of α-emitting nuclides that kill cancer cells and a …

PSMA PET-CT imaging predicts treatment progression in men with biochemically recurrent prostate cancer—a prospective study of men with 3 year follow up

S Ong, C Pascoe, BD Kelly, Z Ballok, D Webb, D Bolton… - Cancers, 2022 - mdpi.com
Simple Summary Prostate-specific membrane antigen (PSMA) positron emission
tomography-computed tomography (PET-CT) is an essential imaging tool that is used to …

[HTML][HTML] Vesicles Secreted by Renal Cell Carcinoma Cells Cause Vascular Endothelial Cells to Express PSMA and Drive Tumor Progression

R Watanabe, K Kagimoto, M Chosei, T Sakaue… - Cells, 2025 - mdpi.com
Prostate-specific membrane antigen (PSMA) protein expression is induced during prostate
cancer progression and metastasis. Recently, we reported that PSMA-positive vesicles …

Melatonin Modulates the SIRT1-Related Pathways via Transdermal Cryopass-Laser Administration in Prostate Tumor Xenograft

F Bonomini, G Favero, A Petroni, R Paroni, R Rezzani - Cancers, 2023 - mdpi.com
Simple Summary The likelihood of prostate tumor diagnosis in men increases with age,
raising the need for novel therapies to better treat this disease. This research examined …