Characterized by their pivotal roles in cell-to-cell communication, cell proliferation, and
immune regulation during tissue repair, exosomes have emerged as a promising avenue for …

Traumatic brain injury (TBI) is a leading cause of death and disability and a global public
health challenge. Every year more than 50 million people suffer a TBI, and it is estimated …

Background Traumatic brain injury (TBI) is a leading cause of disabilities resulting from
cognitive and neurological deficits, as well as psychological disorders. Only recently …

Tau is a protein that has received national mainstream recognition for its potential negative
impact to the brain. This review succinctly provides information on the structure of tau and its …

Polychlorinated biphenyls are ubiquitous environmental contaminants linkedc with
peripheral immune and neural dysfunction. Neuroimmune signaling is critical to brain …

Few translational studies have examined how age-at-injury affects the glial response to
traumatic brain injury (TBI). We hypothesized that rats injured at post-natal day (PND) 17 …

Introduction Severe pediatric traumatic brain injury (spTBI), including abusive head trauma
(AHT) in young children, is a major public health problem. Long-term consequences of …

BackgroundMild traumatic brain injury (mTBI) is common in children. Long-term cognitive
and behavioral outcomes as well as underlying structural brain alterations following …

Hippocampal plasticity is closely related to physiological brain functions such as learning
and memory. However, the effect of toll-like receptor 4 (TLR4) activation on hippocampal …

Both Alzheimer's disease and vascular dementia are the result of disease processes that
typically develop over several decades. Population studies have estimated that more than …