Drug-induced interstitial lung disease

P Spagnolo, P Bonniaud, G Rossi… - European …, 2022 - publications.ersnet.org
Interstitial lung disease (ILD) secondary to drug-induced lung injury is an increasingly
common cause of morbidity and mortality. The number of drugs associated with the …

Cracking the egg: potential of the develo** chicken as a model system for nonclinical safety studies of pharmaceuticals

S Bjørnstad, LPE Austdal, B Roald, JC Glover… - The Journal of …, 2015 - Elsevier
The advance of perinatal medicine has improved the survival of extremely premature
babies, thereby creating a new and heterogeneous patient group with limited information on …

Drug-induced interstitial lung disease: a real-world pharmacovigilance study of the FDA Adverse Event Reporting System from 2004 to 2021

T Jiang, H Su, J Xu, C Li, N Zhang, Y Li… - … Advances in Drug …, 2024 - journals.sagepub.com
Background: Drug-induced interstitial lung disease (DILD) is an increasingly common cause
of morbidity and mortality. However, due to the lack of specificity, DILD detection remains an …

ADMET evaluation in drug discovery. Part 17: development of quantitative and qualitative prediction models for chemical-induced respiratory toxicity

T Lei, F Chen, H Liu, H Sun, Y Kang, D Li… - Molecular …, 2017 - ACS Publications
As a dangerous end point, respiratory toxicity can cause serious adverse health effects and
even death. Meanwhile, it is a common and traditional issue in occupational and …

Protective effects of hesperidin against MTX-induced hepatotoxicity in male albino rats

RM Abdelaziz, AZ Abdelazem, KS Hashem… - … archives of pharmacology, 2020 - Springer
Abstract Hesperidin (HD), a bioflavonoid, has been shown to exert hepatoprotective effects.
Our aim is to investigate the possible protective effects of HD against methotrexate (MTX) …

Acute respiratory distress syndrome mimickers lacking common risk factors of the Berlin definition

A Gibelin, A Parrot, B Maitre, C Brun-Buisson… - Intensive care …, 2016 - Springer
Purpose Some patients presenting with acute respiratory failure and meeting the Berlin
criteria for acute respiratory distress syndrome (ARDS) lack exposure to common risk factors …

Characteristics and prognostic impact of pneumonitis during systemic anti-cancer therapy in patients with advanced non-small-cell lung cancer

D Fujimoto, R Kato, T Morimoto, R Shimizu, Y Sato… - PLoS …, 2016 - journals.plos.org
Background Data on characteristics, outcomes, and prognosis of advanced non-small-cell
lung cancer (NSCLC) patients who develop pneumonitis during systemic anti-cancer …

Development and evaluation of in silico prediction model for drug-induced respiratory toxicity by using naïve Bayes classifier method

H Zhang, JX Ma, CT Liu, JX Ren, L Ding - Food and chemical toxicology, 2018 - Elsevier
Respiratory toxicity is considered as main cause of drug withdrawal, which could seriously
injure human health or even lead to death. The objective of this investigation was to develop …

Diffuse lung diseases ascribed to drugs: a nationwide observational study over 37 years using the French pharmacovigilance database

S Yavordios, G Beltramo, R Freppel… - European …, 2025 - publications.ersnet.org
Background Drug-induced interstitial lung disease (DI-ILD) is a heterogeneous subgroup of
interstitial lung disease (ILD). The number of molecules involved is increasing with time. Due …

Radiological patterns of drug-induced interstitial lung disease (DILD) in early-phase oncology clinical trials

A Terbuch, C Tiu, IM Candilejo, M Scaranti… - Clinical Cancer …, 2020 - aacrjournals.org
Purpose: Drug-induced interstitial lung disease (DILD) is a rare, but potentially fatal toxicity.
Clinical and radiological features of DILD in the early experimental setting are poorly …