25th anniversary article: Rational design and applications of hydrogels in regenerative medicine

N Annabi, A Tamayol, JA Uquillas, M Akbari… - Advanced …, 2014 - Wiley Online Library
Hydrogels are hydrophilic polymer‐based materials with high water content and physical
characteristics that resemble the native extracellular matrix. Because of their remarkable …

Microfluidic tissue engineering and bio‐actuation

M Filippi, T Buchner, O Yasa, S Weirich… - Advanced …, 2022 - Wiley Online Library
Bio‐hybrid technologies aim to replicate the unique capabilities of biological systems that
could surpass advanced artificial technologies. Soft bio‐hybrid robots consist of synthetic …

Digital acoustofluidics enables contactless and programmable liquid handling

SP Zhang, J Lata, C Chen, J Mai, F Guo, Z Tian… - Nature …, 2018 - nature.com
For decades, scientists have pursued the goal of performing automated reactions in a
compact fluid processor with minimal human intervention. Most advanced fluidic handling …

Emerging open microfluidics for cell manipulation

Q Zhang, S Feng, L Lin, S Mao, JM Lin - Chemical Society Reviews, 2021 - pubs.rsc.org
Cell manipulation is the foundation of biochemical studies, which demands user-friendly,
multifunctional and precise tools. Based on flow confinement principles, open microfluidics …

Free‐Boundary Microfluidic Platform for Advanced Materials Manufacturing and Applications

Z Zhu, T Chen, F Huang, S Wang, P Zhu… - Advanced …, 2024 - Wiley Online Library
Microfluidics, with its remarkable capacity to manipulate fluids and droplets at the
microscale, has emerged as a powerful platform in numerous fields. In contrast to …

Bioconjugated hydrogels for tissue engineering and regenerative medicine

S Ahadian, RB Sadeghian, S Salehi… - Bioconjugate …, 2015 - ACS Publications
Hydrogels are hydrophilic polymer networks with high water content, which have played an
important role as scaffolds for cells, as carriers for various biomolecules (eg, drugs, genes …

Engineering microfluidic concentration gradient generators for biological applications

AGG Toh, ZP Wang, C Yang, NT Nguyen - Microfluidics and nanofluidics, 2014 - Springer
This paper reviews the latest developments in the design and fabrication of concentration
gradient generators for microfluidics-based biological applications. New gradient generator …

Recent developments in microfluidics-based chemotaxis studies

J Wu, X Wu, F Lin - Lab on a Chip, 2013 - pubs.rsc.org
Microfluidic devices can better control cellular microenvironments compared to conventional
cell migration assays. Over the past few years, microfluidics-based chemotaxis studies …

Microfluidics in the “open space” for performing localized chemistry on biological interfaces

GV Kaigala, RD Lovchik… - Angewandte Chemie …, 2012 - Wiley Online Library
Local interactions between (bio) chemicals and biological interfaces play an important role
in fields ranging from surface patterning to cell toxicology. These interactions can be studied …

Brain slice on a chip: opportunities and challenges of applying microfluidic technology to intact tissues

Y Huang, JC Williams, SM Johnson - Lab on a Chip, 2012 - pubs.rsc.org
Isolated brain tissue, especially brain slices, are valuable experimental tools for studying
neuronal function at the network, cellular, synaptic, and single channel levels …