Background It is well-established that cancer treatment substantially increases the risk of
long-term adverse health outcomes among childhood cancer survivors. However, there is …

DNA methyltransferase, a key enzyme mediating DNA methylation, is involved in numerous
processes including genomic imprinting, X chromosome inactivation, transposable element …

Cancer stem cells (CSCs) are hypothesized to initiate cancer and give rise to
heterogeneous tumors made up of self-renewing CSCs and the differentiated, less …

Epigenetics is “the study of mitotically and/or meiotically heritable changes in gene function
that cannot be explained by changes in the DNA sequence.” Thus, the same DNA sequence …

摘要DNA 甲基化一直是表观遗传学领域研究的重点之一. 研究表明, DNA
甲基化与胚胎发育以及肿瘤和疾病的发生, 发展密切相关, 因此, DNA 甲基化检测具有重要意义 …

Background: It is well-established that cancer treatment substantially increases the risk of
long-term adverse health outcomes among childhood cancer survivors. However, there is …

In recent years, epigenetic studies have largely concentrated on aging, embryonic
development, and cancer. Presently, epigenetics is found to be important in many other …