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Boolean modeling in systems biology: an overview of methodology and applications
Mathematical modeling of biological processes provides deep insights into complex cellular
systems. While quantitative and continuous models such as differential equations have been …
systems. While quantitative and continuous models such as differential equations have been …
Boolean modeling: a logic‐based dynamic approach for understanding signaling and regulatory networks and for making useful predictions
The biomolecules inside or near cells form a complex interacting system. Cellular
phenotypes and behaviors arise from the totality of interactions among the components of …
phenotypes and behaviors arise from the totality of interactions among the components of …
A node-pinning and state-flipped approach to partial synchronization of Boolean Networks
L Du, Z Zhang, C ** is an effective control method that has just recently been proposed. In this
paper, the state-flipped mechanism is introduced to implement the complete synchronization …
paper, the state-flipped mechanism is introduced to implement the complete synchronization …
A systems biology perspective on plant–microbe interactions: biochemical and structural targets of pathogen effectors
Plants have biochemical defences against stresses from predators, parasites and
pathogens. In this review we discuss the interaction of plant defences with microbial …
pathogens. In this review we discuss the interaction of plant defences with microbial …
State–time spectrum of signal transduction logic models
Despite the current wealth of high-throughput data, our understanding of signal transduction
is still incomplete. Mathematical modeling can be a tool to gain an insight into such …
is still incomplete. Mathematical modeling can be a tool to gain an insight into such …
[KÖNYV][B] PlantOmics: the omics of plant science
The book consists of 29 chapters written by 90 experts from 15 countries that represent three-
fourths of the globe. In the introductory chapter (Chap. 1), Dr. Agrawal and colleagues have …
fourths of the globe. In the introductory chapter (Chap. 1), Dr. Agrawal and colleagues have …
Network model of immune responses reveals key effectors to single and co-infection dynamics by a respiratory bacterium and a gastrointestinal helminth
Co-infections alter the host immune response but how the systemic and local processes at
the site of infection interact is still unclear. The majority of studies on co-infections …
the site of infection interact is still unclear. The majority of studies on co-infections …
Logic modeling in quantitative systems pharmacology
P Traynard, L Tobalina, F Eduati… - CPT …, 2017 - Wiley Online Library
Here we present logic modeling as an approach to understand deregulation of signal
transduction in disease and to characterize a drug's mode of action. We discuss how to build …
transduction in disease and to characterize a drug's mode of action. We discuss how to build …
Computational and experimental analysis reveals a requirement for eosinophil-derived IL-13 for the development of allergic airway responses in C57BL/6 mice
ER Walsh, J Thakar, K Stokes, F Huang… - The Journal of …, 2011 - journals.aai.org
Eosinophils are found in the lungs of humans with allergic asthma, as well as in the lungs of
animals in models of this disease. Increasing evidence suggests that these cells are integral …
animals in models of this disease. Increasing evidence suggests that these cells are integral …