The role of neuroactive steroids in tic disorders

C Branca, M Bortolato - Neuroscience & Biobehavioral Reviews, 2024 - Elsevier
Tics are sudden, repetitive movements or vocalizations. Tic disorders, such as Tourette
syndrome (TS), are contributed by the interplay of genetic risk factors and environmental …

[HTML][HTML] Genetic advances and translational phenotypes in rodent models for Tourette disorder

TF Kowalski, R Wang, MA Tischfield - Current Opinion in Neurobiology, 2025 - Elsevier
Tourette disorder (TD) is a neurodevelopmental condition affecting approximately 0.3%–1%
of children and adolescents. It is defined by motor and vocal tics but encompasses wide …

Antioxidant Behavioural Phenotype in the Immp2l Gene Knock-Out Mouse

AJ Lawther, J Zieba, Z Fang, TM Furlong, I Conn… - Genes, 2023 - mdpi.com
Mitochondrial dysfunction is strongly associated with autism spectrum disorder (ASD) and
the Inner mitochondrial membrane protein 2-like (IMMP2L) gene is linked to autism …

[HTML][HTML] Hippocampal neuroinflammation induced by lipopolysaccharide causes sex-specific disruptions in action selection, food approach memories, and neuronal …

K Ganesan, S Ghorbanpour, W Kendall… - Brain, Behavior, and …, 2025 - Elsevier
Hippocampal neuroinflammation is present in multiple diseases and disorders that impact
motivated behaviour in a sex-specific manner, but whether neuroinflammation alone is …

[HTML][HTML] Immp2l Deficiency Induced Granulosa Cell Senescence Through STAT1/ATF4 Mediated UPRmt and STAT1/(ATF4)/HIF1α/BNIP3 Mediated Mitophagy …

X Qu, P Pan, S Cao, Y Ma, J Yang, H Gao… - International Journal of …, 2024 - mdpi.com
Dysfunctional mitochondria producing excessive ROS are the main factors that cause
ovarian aging. Immp2l deficiency causes mitochondrial dysfunction and excessive ROS …

Immp2l Enhances the Structure and Function of Mitochondrial Gpd2 Dehydrogenase

RA Clarke, H Govindaraju, M Beretta… - International Journal of …, 2024 - mdpi.com
'Inner mitochondrial membrane peptidase 2 like'(IMMP2L) is a nuclear-encoded
mitochondrial peptidase that has been conserved through evolutionary history, as has its …

Hippocampal neuroinflammation causes sex-specific disruptions in action selection, food approach memories, and neuronal excitation

K Ganesan, S Ghorbanpour, W Kendall, ST Broome… - bioRxiv, 2024 - biorxiv.org
Hippocampal neuroinflammation is present in multiple diseases and disorders that impact
motivated behaviour in a sex-specific manner, but whether neuroinflammation alone is …

IMMP2L Peptidase Enhances the Structure and Function of Mitochondrial GPD2 Dehydrogenase.

RA Clarke, H Govindaraju, M Beretta, E Olzomer… - 2023 - preprints.org
Abstract 'Inner mitochondrial membrane peptidase 2 like'(IMMP2L) is a nuclear encoded
mitochondrial peptidase that has been conserved through evolutionary history as has its …