Vanadium in biological action: chemical, pharmacological aspects, and metabolic implications in diabetes mellitus

S Treviño, A Díaz, E Sánchez-Lara… - Biological trace element …, 2019 - Springer
Vanadium compounds have been primarily investigated as potential therapeutic agents for
the treatment of various major health issues, including cancer, atherosclerosis, and …

The chemistry and biochemistry of vanadium and the biological activities exerted by vanadium compounds

DC Crans, JJ Smee, E Gaidamauskas… - Chemical reviews, 2004 - ACS Publications
Vanadium is a trace element, which may be beneficial and possibly essential in humans1
but certainly essential for some living organisms. 2r11 Metal ions and thus vanadium ions …

Hydrolysis, Ligand Exchange, and Redox Properties of Vanadium Compounds: Implications of Solution Transformation on Biological, Therapeutic, and Environmental …

R Dinda, E Garribba, D Sanna, DC Crans… - Chemical …, 2025 - ACS Publications
Vanadium is a transition metal with important industrial, technological, biological, and
biomedical applications widespread in the environment and in living beings. The different …

In vitro study of the insulin-mimetic behaviour of vanadium (IV, V) coordination compounds

D Rehder, J Costa Pessoa, CF Geraldes… - JBIC Journal of …, 2002 - Springer
A representative set of vanadium (IV and V) compounds in varying coordination
environments has been tested in the concentration range 1 to 10–6 mM, using transformed …

Separation and recovery of vanadium and aluminum from oxalic acid leachate of shale by solvent extraction with Aliquat 336

Z Liu, J Huang, Y Zhang, T Liu, P Hu, H Liu… - Separation and …, 2020 - Elsevier
The solvent extraction of vanadium has been widely studied in inorganic acid systems; but
less in organic acid systems. In this study, the separation and recovery of vanadium and …

Biospeciation of antidiabetic VO (IV) complexes

T Kiss, T Jakusch, D Hollender, Á Dörnyei… - Coordination Chemistry …, 2008 - Elsevier
The possible transformations of antidiabetic vanadium (IV) complexes in the organism are
discussed. These reactions involve absorption processes in the gastrointestinal tract …

Preparation and characterization of vanadyl complexes with bidentate maltol-type ligands; in vivo comparisons of anti-diabetic therapeutic potential

KH Thompson, BD Liboiron, Y Sun, KD Bellman… - JBIC Journal of …, 2003 - Springer
A series of 2-alkyl-3-hydroxy-4-pyrone oxovanadium (IV) compounds has been synthesized,
characterized, and tested for bioactivity as potential insulin-enhancing agents. The vanadyl …

Speciation in human blood of Metvan, a vanadium based potential anti-tumor drug

D Sanna, V Ugone, G Micera, P Buglyó, L Bíró… - Dalton …, 2017 - pubs.rsc.org
The first report on the anti-cancer activity of the compound Metvan,[VIVO (Me2phen) 2
(SO4)], where Me2phen is 4, 7-dimethyl-1, 10-phenanthroline, dates back to 2001. Although …

The speciation of vanadium in human serum

T Jakusch, JC Pessoa, T Kiss - Coordination Chemistry Reviews, 2011 - Elsevier
A knowledge of the speciation of vanadium in human serum is essential for an
understanding of the biotransformation of antidiabetic vanadium complexes in human blood …

Pyrone derivatives and metals: From natural products to metal-based drugs

W Kandioller, A Kurzwernhart, M Hanif… - Journal of …, 2011 - Elsevier
Pyrone scaffolds are often present in natural products and many derivatives therefore exhibit
favorable biocompatibility and toxicity profiles. Hydroxypyrones are obtained from natural …