Vitamin D signaling in the bovine immune system: a model for understanding human vitamin D requirements
The endocrine physiology of vitamin D in cattle has been rigorously investigated and has
yielded information on vitamin D requirements, endocrine function in health and disease …
yielded information on vitamin D requirements, endocrine function in health and disease …
Host Response to Leptospira Infection
RL Zuerner - Leptospira and Leptospirosis, 2014 - Springer
Pathogenic Leptospira has the capacity to infect a broad range of mammalian hosts.
Leptospirosis may appear as an acute, potentially fatal infection in accidental hosts, or …
Leptospirosis may appear as an acute, potentially fatal infection in accidental hosts, or …
γδ T cell function varies with the expressed WC1 coreceptor
AN Rogers, DG VanBuren, EE Hedblom… - The Journal of …, 2005 - journals.aai.org
WC1 molecules are transmembrane glycoproteins belonging to the scavenger receptor
cysteine-rich family and uniquely expressed on γδ T cells. Although participation of WC1+ γδ …
cysteine-rich family and uniquely expressed on γδ T cells. Although participation of WC1+ γδ …
Subpopulations of bovine WC1+ γδ T cells rather than CD4+ CD25highFoxp3+ T cells act as immune regulatory cells ex vivo
A Hoek, VPMG Rutten, J Kool… - Veterinary …, 2008 - pmc.ncbi.nlm.nih.gov
Regulatory T cells (Treg) are regarded essential components for maintenance of immune
homeostasis. Especially CD4+ CD25high T cells are considered to be important regulators …
homeostasis. Especially CD4+ CD25high T cells are considered to be important regulators …
Characterization of the domestic goat γδ T cell receptor gene loci and gene usage
Goats and cattle diverged 30 million years ago but retain similarities in immune system
genes. Here, the caprine T cell receptor (TCR) gene loci and transcription of its genes were …
genes. Here, the caprine T cell receptor (TCR) gene loci and transcription of its genes were …
Subset-specific, uniform activation among Vγ6/Vδ1+ γδ T cells elicited by inflammation
CL Roark, MK Aydintug, J Lewis, X Yin… - Journal of Leucocyte …, 2004 - academic.oup.com
The Vγ6/Vδ1+ cells, the second murine γδ T cell subset to arise in the thymus, express a
nearly invariant T cell receptor (TCR), colonize select tissues, and expand preferentially in …
nearly invariant T cell receptor (TCR), colonize select tissues, and expand preferentially in …
A Leptospira borgpetersenii serovar Hardjo vaccine induces a Th1 response, activates NK cells, and reduces renal colonization
RL Zuerner, DP Alt, MV Palmer… - Clinical and vaccine …, 2011 - Am Soc Microbiol
Chronic infection of cattle with Leptospira borgpetersenii serovar Hardjo reduces animal
production through reproductive failure and presents a persistent health threat to workers in …
production through reproductive failure and presents a persistent health threat to workers in …
Evaluation of protective immunity of Leptospira immunoglobulin like protein A (LigA) DNA vaccine against challenge in hamsters
SM Faisal, WW Yan, CS Chen, RUM Palaniappan… - Vaccine, 2008 - Elsevier
We demonstrated earlier that immunization with recombinant Leptospira immunoglobulin
like protein A (LigA) induced significant protection against virulent Leptospira interrogans …
like protein A (LigA) induced significant protection against virulent Leptospira interrogans …
Comparison of three different leptospiral vaccines for induction of a type 1 immune response to Leptospira borgpetersenii serovar Hardjo
Leptospira serovar Hardjo are bacterial pathogens of cattle that cause zoonotic infections of
humans. Monovalent serovar Hardjo vaccines protect cattle from serovar Hardjo while …
humans. Monovalent serovar Hardjo vaccines protect cattle from serovar Hardjo while …
Leptospira interrogans activation of human peripheral blood mononuclear cells: preferential expansion of TCRγδ+ T cells vs TCRαβ+ T cells
Innate and adaptive immune responses induced by leptospirosis have not been well
characterized. In this study we show that in vitro exposure of naive human PBMC to …
characterized. In this study we show that in vitro exposure of naive human PBMC to …