Accumulating evidence indicates that gut transit time is a key factor in sha** the gut
microbiota composition and activity, which are linked to human health. Both population-wide …

Abstract The Japanese Society of Gastroenterology first published evidence-based clinical
practice guidelines for cholelithiasis in 2010, followed by a revision in 2016. Currently, the …

The present study aims to evaluate the probiotic potential of lactic acid bacteria (LAB)
isolated from naturally fermented olives and select candidates to be used as probiotic …

Probiotics are defined as “living microorganisms, which upon ingestion in certain numbers
exert health benefits on the host beyond inherent basic nutrition”(43). Various studies have …

Summary With a prevalence of 10–15% in adults in Europe and the USA, gallstones are the
most common digestive disease needing admission to hospital in the West. The interplay …

Bile salts play crucial roles in allowing the gastrointestinal system to digest, transport and
metabolize nutrients. They function as nutrient signaling hormones by activating specific …

Gallstone disease (GSD) has, for many years, remained a high-cost, socially significant
public health problem. Over the past decade, a number of studies have been carried out …

Gallstone disease is one of the most prevalent gastrointestinal diseases with a substantial
burden to health care systems that is supposed to increase in ageing populations at risk …

The ileal apical sodium bile acid cotransporter participates in the enterohepatic circulation of
bile acids. In patients with primary bile acid malabsorption, mutations in the ileal bile acid …

Gallstone disease is very common in the Western world with an estimated prevalence of
10% to 15% in white adults, leading to significant morbidity, mortality, and considerable …