Optic neuritis

AT Toosy, DF Mason, DH Miller - The Lancet Neurology, 2014‏ - thelancet.com
Acute optic neuritis is the most common optic neuropathy affecting young adults. Exciting
developments have occurred over the past decade in understanding of optic neuritis …

Optical coherence tomography as retinal imaging biomarker of neuroinflammation/neurodegeneration in systemic disorders in adults and children

S Vujosevic, MM Parra, ME Hartnett, L O'Toole, A Nuzzi… - Eye, 2023‏ - nature.com
The retina and the optic nerve are considered extensions of the central nervous system
(CNS) and thus can serve as the window for evaluation of CNS disorders. Spectral domain …

Optical coherence tomography reflects brain atrophy in multiple sclerosis: a four‐year study

S Saidha, O Al‐Louzi, JN Ratchford… - Annals of …, 2015‏ - Wiley Online Library
Objective The aim of this work was to determine whether atrophy of specific retinal layers
and brain substructures are associated over time, in order to further validate the utility of …

Imaging retina to study dementia and stroke

CY Cheung, MK Ikram, C Chen, TY Wong - Progress in retinal and eye …, 2017‏ - Elsevier
With increase in life expectancy, the number of persons suffering from common age-related
brain diseases, including neurodegenerative (eg, dementia) and cerebrovascular (eg …

Retinal layer segmentation in multiple sclerosis: a systematic review and meta-analysis

A Petzold, LJ Balcer, PA Calabresi, F Costello… - The Lancet …, 2017‏ - thelancet.com
Background Structural retinal imaging biomarkers are important for early recognition and
monitoring of inflammation and neurodegeneration in multiple sclerosis. With the …

Optical coherence tomography in multiple sclerosis: a 3‐year prospective multicenter study

F Paul, PA Calabresi, F Barkhof… - Annals of clinical …, 2021‏ - Wiley Online Library
Objective To evaluate changes over 3 years in the thickness of inner retinal layers including
the peripapillary retinal nerve fiber layer (pRNFL), and combined macular ganglion cell and …

Quality control for retinal OCT in multiple sclerosis: validation of the OSCAR-IB criteria

S Schippling, LJ Balk, F Costello… - Multiple sclerosis …, 2015‏ - journals.sagepub.com
Background: Retinal optical coherence tomography (OCT) permits quantification of retinal
layer atrophy relevant to assessment of neurodegeneration in multiple sclerosis (MS) …

Retinal layer segmentation of macular OCT images using boundary classification

A Lang, A Carass, M Hauser, ES Sotirchos… - Biomedical optics …, 2013‏ - opg.optica.org
Optical coherence tomography (OCT) has proven to be an essential imaging modality for
ophthalmology and is proving to be very important in neurology. OCT enables high …

Neuromyelitis optica and multiple sclerosis: seeing differences through optical coherence tomography

JL Bennett, J de Seze, M Lana-Peixoto… - Multiple Sclerosis …, 2015‏ - journals.sagepub.com
Neuromyelitis optica (NMO) is an inflammatory autoimmune disease of the central nervous
system that preferentially targets the optic nerves and spinal cord. The clinical presentation …

Past, present and future role of retinal imaging in neurodegenerative disease

AH Kashani, S Asanad, JW Chan, MB Singer… - Progress in retinal and …, 2021‏ - Elsevier
Retinal imaging technology is rapidly advancing and can provide ever-increasing amounts
of information about the structure, function and molecular composition of retinal tissue in …