Molecular predictors of clinical outcome in patients with head and neck squamous cell carcinoma

GR Thomas, H Nadiminti… - International journal of …, 2005 - Wiley Online Library
Head and neck squamous cell carcinoma (HNSCC) involves the upper aerodigestive tract
and can destroy the structure and function of organs involved in voice, speech, taste, smell …

Cellular roles of ADAM12 in health and disease

M Kveiborg, R Albrechtsen, JR Couchman… - The international journal …, 2008 - Elsevier
ADAM12 belongs to the large family of ADAMs (a disintegrin and metalloproteases) and
possesses extracellular metalloprotease and cell-binding functions, as well as intracellular …

Identification of differentially expressed genes in HPV-positive and HPV-negative oropharyngeal squamous cell carcinomas

I Martinez, J Wang, KF Hobson, RL Ferris… - European journal of …, 2007 - Elsevier
Human papillomaviruses (HPVs) have been implicated in the pathogenesis of a subset of
squamous cell carcinoma of the head and neck (SCCHN). The goal of this study was to …

Expression profiles and clinical correlations of degradome components in the tumor microenvironment of head and neck squamous cell carcinoma

A Stokes, J Joutsa, R Ala-Aho, M Pitchers… - Clinical cancer …, 2010 - AACR
Purpose: Head and neck squamous cell carcinomas (HNSCC) are characterized by high
morbidity and mortality, largely due to the high invasive and metastatic potential of these …

Disease mechanism and biomarkers of oral squamous cell carcinoma

BMN Brinkman, DTW Wong - Current opinion in oncology, 2006 - journals.lww.com
Important progress has been made in the molecular understanding of oral cancer and its
application for diagnosis, prognosis and treatment. The increased efforts in translational …

EMP1, EMP 2, and EMP3 as novel therapeutic targets in human cancer

YW Wang, HL Cheng, YR Ding, LH Chou… - Biochimica et Biophysica …, 2017 - Elsevier
The epithelial membrane protein genes 1, 2, and 3 (EMP1, EMP2, and EMP3) belong to the
peripheral myelin protein 22-kDa (PMP22) gene family, which consists of at least seven …

The role of the histone demethylase KDM4A in cancer

L Guerra-Calderas, R González-Barrios, LA Herrera… - Cancer genetics, 2015 - Elsevier
Histone posttranslational modifications are important components of epigenetic regulation.
One extensively studied modification is the methylation of lysine residues. These …

The MAL protein, an integral component of specialized membranes, in normal cells and cancer

A Rubio-Ramos, L Labat-de-Hoz, I Correas, MA Alonso - Cells, 2021 - mdpi.com
The MAL gene encodes a 17-kDa protein containing four putative transmembrane segments
whose expression is restricted to human T cells, polarized epithelial cells and myelin …

Parathyroid hormone-related protein serves as a prognostic indicator in oral squamous cell carcinoma

Z Lv, X Wu, W Cao, ZZ Shen, L Wang, FR **e… - Journal of Experimental …, 2014 - Springer
Background In our previous study, parathyroid hormone-like hormone (PTHLH) which
encodes parathyroid hormone-related protein (PTHrP) was revealed to be up-regulated in …

The disintegrin and metalloprotease ADAM12 is associated with TGF-β-induced epithelial to mesenchymal transition

M Ruff, A Leyme, F Le Cann, D Bonnier, J Le Seyec… - PLoS …, 2015 - journals.plos.org
The increased expression of the Disintegrin and Metalloprotease ADAM12 has been
associated with human cancers, however its role remain unclear. We have previously …