Mesocorticolimbic dopamine circuity undergoes a protracted maturation during adolescent
life. Stable adult levels of behavioral functioning in reward, motivational, and cognitive …

Highlights•Different forms of cognitive flexibility show dissociable developmental
trajectories.•An adolescent-specific mode of flexibility scaffolds adult-like cognitive …

Animal and human postmortem studies provide evidence for changes in gamma-
aminobutyric acid (GABA) and glutamate in prefrontal cortex (PFC) during adolescence …

Extensive investigations spanning multiple levels of inquiry, from genetic to behavioural
studies, have sought to unravel the mechanistic foundations of attention-deficit hyperactivity …

Anhedonia, or diminished pleasure and motivation, is a symptom of severe mental illness
(eg, depressive disorder, bipolar disorder, schizophrenia) that emerges during adolescence …

Across the lifespan, individuals frequently choose between exploiting known rewarding
options or exploring unknown alternatives. A large body of work has suggested that children …

Converging evidence from both human neuroimaging and animal studies has supported a
model of mesolimbic processing underlying reward learning behaviors, based on the …

Abstract The ongoing Chinese Color Nest Project (CCNP) was established to create
normative charts for brain structure and function across the human lifespan, and link age …

Across development, interactions between value-based learning and memory processes
promote the formation of mental models that enable flexible goal pursuit. Value cues in the …

Background Iron is essential to brain function, and iron deficiency during youth may
adversely impact neurodevelopment. Understanding the developmental time course of iron …