Neisserial surface lipoproteins: structure, function and biogenesis
The surface of many Gram-negative bacteria contains lipidated protein molecules referred to
as surface lipoproteins or SLPs. SLPs play critical roles in host immune evasion, nutrient …
as surface lipoproteins or SLPs. SLPs play critical roles in host immune evasion, nutrient …
Identification of Putative Vaccine and Drug Targets against the Methicillin-Resistant Staphylococcus aureus by Reverse Vaccinology and Subtractive Genomics …
Methicillin-resistant Staphylococcus aureus (MRSA) is an opportunistic pathogen and
responsible for causing life-threatening infections. The emergence of hypervirulent and …
responsible for causing life-threatening infections. The emergence of hypervirulent and …
Update on the Neisseria Macrophage Infectivity Potentiator-Like PPIase Protein
M Christodoulides - Frontiers in Cellular and Infection Microbiology, 2022 - frontiersin.org
Neisseria pathogens express a Macrophage Infectivity Potentiator Protein (MIP), which
belongs to the FK506 binding protein (FKBP) family of proteins that exhibit peptidyl-prolyl …
belongs to the FK506 binding protein (FKBP) family of proteins that exhibit peptidyl-prolyl …
Investigation of cross-opsonic effect leads to the discovery of PPIase-domain containing protein vaccine candidate to prevent infections by Gram-positive ESKAPE …
Abstract Background Enterococcus faecium and Staphylococcus aureus are the Gram-
positive pathogens of the ESKAPE group, known to represent a great threat to human health …
positive pathogens of the ESKAPE group, known to represent a great threat to human health …
High Affinity Inhibitors of the Macrophage Infectivity Potentiator Protein from Trypanosoma cruzi, Burkholderia pseudomallei, and Legionella pneumophila─A …
T Lohr, C Herbst, NM Bzdyl, C Jenkins… - ACS Infectious …, 2024 - ACS Publications
Since Chagas disease, melioidosis, and Legionnaires' disease are all potentially life-
threatening infections, there is an urgent need for new treatment strategies. All causative …
threatening infections, there is an urgent need for new treatment strategies. All causative …
Genetic variants linked to the phenotypic outcome of invasive disease and carriage of Neisseria meningitidis
L Eriksson, TB Johannesen, B Stenmark… - Microbial …, 2023 - microbiologyresearch.org
Neisseria meningitidis can be a human commensal in the upper respiratory tract but is also
capable of causing invasive diseases such as meningococcal meningitis and septicaemia …
capable of causing invasive diseases such as meningococcal meningitis and septicaemia …
The macrophage infectivity potentiator of Trypanosoma cruzi induces innate IFN-γ and TNF-α production by human neonatal and adult blood cells through TLR2/1 …
S Ait Djebbara, S Mcheik, P Percier, N Segueni… - Frontiers in …, 2023 - frontiersin.org
We previously identified the recombinant (r) macrophage (M) infectivity (I) potentiator (P) of
the protozoan parasite Trypanosoma cruzi (Tc)(rTcMIP) as an immuno-stimulatory protein …
the protozoan parasite Trypanosoma cruzi (Tc)(rTcMIP) as an immuno-stimulatory protein …
Inhibitors of macrophage infectivity potentiator-like PPIases affect neisserial and chlamydial pathogenicity
A Reimer, F Seufert, M Weiwad, J Ebert… - International journal of …, 2016 - Elsevier
The pathogenic bacteria Chlamydia trachomatis, Neisseria gonorrhoeae and Neisseria
meningitidis express the surface-exposed macrophage infectivity potentiator (MIP)-like …
meningitidis express the surface-exposed macrophage infectivity potentiator (MIP)-like …
Peptidyl isomerase PrsA is surface-associated on Streptococcus suis and offers cross-protection against serotype 9 strain
X Jiang, Y Yang, J Zhou, H Liu, X Liao… - FEMS microbiology …, 2019 - academic.oup.com
PrsA, a peptidyl isomerase encoded by the prsA gene, plays pleiotropic roles in bacterial
physiology and pathogenicity. This study was attempted to characterize the distribution of …
physiology and pathogenicity. This study was attempted to characterize the distribution of …
Macrophage-infectivity potentiator of Trypanosoma cruzi (TcMIP) is a new pro-type 1 immuno-stimulating protein for neonatal human cells and vaccines in mice
M Radwanska, F de Lemos Esteves, L Linsen… - Frontiers in …, 2023 - frontiersin.org
This work identifies the protein “macrophage infectivity potentiator” of Trypanosoma cruzi
trypomastigotes, as supporting a new property, namely a pro-type 1 immunostimulatory …
trypomastigotes, as supporting a new property, namely a pro-type 1 immunostimulatory …