Atopic dermatitis is a chronic inflammatory skin disease associated with cutaneous
hyperreactivity to environmental triggers and is often the first step in the atopic march that …

There are remarkable differences in the diagnostic and therapeutic management of atopic
dermatitis practiced by dermatologists and pediatricians in different countries. Therefore, the …

The mechanisms by which immune responses to nonpathogenic environmental antigens
lead to either allergy or nonharmful immunity are unknown. Single allergen-specific T cells …

▪ Abstract When asthma is diagnosed, eosinophilic inflammation and airway remodeling are
established in the bronchial airways and can no longer be separated as cause and effect …

BACKGROUND: IL-31 is a newly discovered T-cell cytokine that, when overexpressed in
mice, results in pruritus and skin dermatitis resembling human atopic dermatitis (AD) …

This review provides an overview of the inflammatory mechanisms and immunological
aspects specific to atopic dermatitis. The review discusses publications on the roles of …

Pollen grains induce allergies in susceptible individuals by release of allergens upon
contact with mucosal membranes of the upper respiratory tract. We recently demonstrated …

Advances in understanding of the immune microenvironment have highlighted the role of
immunosuppressive T cell, myeloid, dendritic and monocytic sub-populations in inhibition of …

The question “What makes an allergen an allergen?” has puzzled generations of
researchers, and we still do not have a conclusive answer. Despite increasing knowledge …

Advances have been made in defining the mechanisms for the control of allergic airway
inflammation in response to inhaled antigens. Several genes, including ADAM33, DPP10 …