DNA as a universal chemical substrate for computing and data storage

S Yang, BWA Bögels, F Wang, C Xu, H Dou… - Nature Reviews …, 2024 - nature.com
DNA computing and DNA data storage are emerging fields that are unlocking new
possibilities in information technology and diagnostics. These approaches use DNA …

Learning without neurons in physical systems

M Stern, A Murugan - Annual Review of Condensed Matter …, 2023 - annualreviews.org
Learning is traditionally studied in biological or computational systems. The power of
learning frameworks in solving hard inverse problems provides an appealing case for the …

Pattern recognition in the nucleation kinetics of non-equilibrium self-assembly

CG Evans, J O'Brien, E Winfree, A Murugan - Nature, 2024 - nature.com
Inspired by biology's most sophisticated computer, the brain, neural networks constitute a
profound reformulation of computational principles,–. Analogous high-dimensional, highly …

Implementing digital computing with DNA-based switching circuits

F Wang, H Lv, Q Li, J Li, X Zhang, J Shi, L Wang… - Nature …, 2020 - nature.com
DNA strand displacement reactions (SDRs) provide a set of intelligent toolboxes for
develo** molecular computation. Whereas SDR-based logic gate circuits have achieved a …

Molecular computation for molecular classification

C Kieffer, AJ Genot, Y Rondelez, G Gines - Advanced Biology, 2023 - Wiley Online Library
DNA as an informational polymer has, for the past 30 years, progressively become an
essential molecule to rationally build chemical reaction networks endowed with powerful …

Building a community to engineer synthetic cells and organelles from the bottom-up

O Staufer, JA De Lora, E Bailoni, A Bazrafshan… - Elife, 2021 - elifesciences.org
Employing concepts from physics, chemistry and bioengineering,'learning-by-
building'approaches are becoming increasingly popular in the life sciences, especially with …

Design and implementation of pavlovian associative memory based on DNA neurons

J Sun, W Xu, P Liu, Y Wang - IEEE Transactions on Neural …, 2024 - ieeexplore.ieee.org
In the field of biocomputing and neural networks, deoxyribonucleic acid (DNA) strand
displacement (DSD) technology performs well in computation, programming, and …

Chemical neural networks inside synthetic cells? A proposal for their realization and modeling

PL Gentili, P Stano - Frontiers in Bioengineering and Biotechnology, 2022 - frontiersin.org
The exciting sci-tech arena of synthetic biology (SB) provides concepts, tools, and
approaches for fundamental revolutions in basic and applied research. SB plays a key role …

Information processing based on DNA toehold-mediated strand displacement (TMSD) reaction

T Luo, S Fan, Y Liu, J Song - Nanoscale, 2021 - pubs.rsc.org
SemiSynBio is an emerging topic toward the construction of platforms for next-generation
information processing. Recent research has indicated its promising prospect toward …

Feedforward Chemical Neural Network: An In Silico Chemical System That Learns xor

D Blount, P Banda, C Teuscher, D Stefanovic - Artificial life, 2017 - direct.mit.edu
Inspired by natural biochemicals that perform complex information processing within living
cells, we design and simulate a chemically implemented feedforward neural network, which …