Abstract Type IV P-type ATPases (P4-ATPases) are a family of transmembrane enzymes that
translocate lipid substrates from the outer to the inner leaflet of biological membranes and …

Cerebral small vessel disease (SVD) is a vascular disorder that increases the risk of stroke
and dementia and is diagnosed through brain MRI. Current primary prevention and …

Cerebral small vessel disease (cSVD) causes lacunar stroke (25% of ischaemic strokes),
haemorrhage, dementia, physical frailty, or is 'covert', but has no specific treatment …

This aim of this editorial is to highlight progress made in brain barrier and brain fluid
research in 2022. It covers studies on the blood-brain, blood-retina and blood-CSF barriers …

Phosphatidylserine (PS) is a common type of phospholipid, typically located in the inner
leaflet of the cell membrane, especially abundant in the nervous system. It is an important …

The myelinated white matter tracts of the central nervous system (CNS) are essential for fast
transmission of electrical impulses and are often differentially affected in human …

Although dementia research has been dominated by Alzheimer's disease (AD), most
dementia in older people is now recognised to be due to mixed pathologies, usually …

White matter injury is a progressive vascular disease that leads to neurological deficits and
vascular dementia. It comprises up to 30% of all diagnosed strokes, though up to ten times …

Cerebrovascular disease is the second most common cause of cognitive disorders, usually
referred to as vascular contributions to cognitive impairment and dementia (VCID) and …

Chronic arterial hypertension causes cerebral microvascular dysfunction and doubles
dementia risk in aging. However, cognitive health preservation by therapeutic blood …