Natural killer cells: development, maturation, and clinical utilization
AM Abel, C Yang, MS Thakar… - Frontiers in …, 2018 - frontiersin.org
Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-
tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells …
tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells …
NK cell recognition
LL Lanier - Annu. Rev. Immunol., 2005 - annualreviews.org
NK CELL RECOGNITION | Annual Reviews Menu Publications AZ Journal Information About
Subscribe Give Personal Register/Sign-in 0 Cart Help Journal Information Author Resource …
Subscribe Give Personal Register/Sign-in 0 Cart Help Journal Information Author Resource …
Activating and inhibitory receptors of natural killer cells
HJ Pegram, DM Andrews, MJ Smyth… - Immunology and cell …, 2011 - Wiley Online Library
Natural killer (NK) cells are potent immune effector cells that can respond to infection and
cancer, as well as allowing maternal adaptation to pregnancy. In response to malignant …
cancer, as well as allowing maternal adaptation to pregnancy. In response to malignant …
Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis
Natural killer cells can discriminate between normal cells and cells that do not express
adequate amounts of major histocompatibility complex (MHC) class I molecules. The …
adequate amounts of major histocompatibility complex (MHC) class I molecules. The …
A comprehensive review on the role of co-signaling receptors and Treg homeostasis in autoimmunity and tumor immunity
The immune system ensures optimum T-effector (Teff) immune responses against invading
microbes and tumor antigens while preventing inappropriate autoimmune responses …
microbes and tumor antigens while preventing inappropriate autoimmune responses …
Regulation of cutaneous malignancy by γδ T cells
M Girardi, DE Oppenheim, CR Steele, JM Lewis… - Science, 2001 - science.org
The localization of γδ T cells within epithelia suggests that these cells may contribute to the
down-regulation of epithelial malignancies. We report that mice lacking γδ cells are highly …
down-regulation of epithelial malignancies. We report that mice lacking γδ cells are highly …
Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion
Freshly isolated, resting natural killer (NK) cells are generally less lytic against target cells
than in vitro interleukin 2 (IL-2)-activated NK cells. To investigate the basis for this difference …
than in vitro interleukin 2 (IL-2)-activated NK cells. To investigate the basis for this difference …
NK cells and cancer immunosurveillance
I Waldhauer, A Steinle - Oncogene, 2008 - nature.com
Natural killer (NK) cells are lymphocytes of the innate immune system that monitor cell
surfaces of autologous cells for an aberrant expression of MHC class I molecules and cell …
surfaces of autologous cells for an aberrant expression of MHC class I molecules and cell …
Natural killer cells, viruses and cancer
A Cerwenka, LL Lanier - Nature reviews immunology, 2001 - nature.com
Natural killer cells are innate immune cells that control certain microbial infections and
tumours. The function of natural killer cells is regulated by a balance between signals …
tumours. The function of natural killer cells is regulated by a balance between signals …
Activation, coactivation, and costimulation of resting human natural killer cells
Natural killer (NK) cells possess potent perforin‐and interferon‐γ‐dependent effector
functions that are tightly regulated. Inhibitory receptors for major histocompatibility complex …
functions that are tightly regulated. Inhibitory receptors for major histocompatibility complex …