Acute kidney injury as a condition of renal senescence
Acute kidney injury (AKI), characterized by a sharp drop in glomerular filtration, continues to
be a significant health burden because it is associated with high initial mortality, morbidity …
be a significant health burden because it is associated with high initial mortality, morbidity …
Mesenchymal stem cell therapy for diabetic kidney disease: a review of the studies using syngeneic, autologous, allogeneic, and xenogeneic cells
Diabetic kidney disease (DKD) is a microvascular complication of diabetes mellitus (DM)
and comprises multifactorial pathophysiologic mechanisms. Despite current treatment …
and comprises multifactorial pathophysiologic mechanisms. Despite current treatment …
Quercetin protects against cisplatin‐induced acute kidney injury by inhibiting Mincle/Syk/NF‐κB signaling maintained macrophage inflammation
RZ Tan, C Wang, C Deng, X Zhong, Y Yan… - Phytotherapy …, 2020 - Wiley Online Library
Acute kidney injury (AKI) with high incidence and mortality is the main cause of chronic
kidney disease. Previous studies have indicated that quercetin, an abundant flavonoid in …
kidney disease. Previous studies have indicated that quercetin, an abundant flavonoid in …
Artesunate relieves acute kidney injury through inhibiting macrophagic Mincle‐mediated necroptosis and inflammation to tubular epithelial cell
X Lei, R Tan, J Jia, S Wu, C Wen, X Lin… - Journal of Cellular …, 2021 - Wiley Online Library
Artesunate is a widely used derivative of artemisinin for malaria. Recent researches have
shown that artesunate has a significant anti‐inflammatory effect on many diseases …
shown that artesunate has a significant anti‐inflammatory effect on many diseases …
Sorafenib cardiotoxicity increases mortality after myocardial infarction
JM Duran, CA Makarewich, D Trappanese… - Circulation …, 2014 - Am Heart Assoc
Rationale: Sorafenib is an effective treatment for renal cell carcinoma, but recent clinical
reports have documented its cardiotoxicity through an unknown mechanism. Objective …
reports have documented its cardiotoxicity through an unknown mechanism. Objective …
[HTML][HTML] Calycosin pretreatment enhanced the therapeutic efficacy of mesenchymal stem cells to alleviate unilateral ureteral obstruction-induced renal fibrosis by …
Q Hu, B Zhu, G Yang, J Jia, H Wang, R Tan… - Journal of …, 2023 - Elsevier
Bone marrow-derived mesenchymal stem cells (MSCs) show antifibrotic activity in various
chronic kidney diseases. Here, we aimed to investigate whether Calycosin (CA), a …
chronic kidney diseases. Here, we aimed to investigate whether Calycosin (CA), a …
Therapeutic potential of mesenchymal stem cells in a pre-clinical model of diabetic kidney disease and obesity
C Sávio-Silva, PE Soinski-Sousa… - International journal of …, 2021 - mdpi.com
Diabetic kidney disease (DKD) is a worldwide microvascular complication of type 2 diabetes
mellitus (T2DM). From several pathological mechanisms involved in T2DM-DKD, we …
mellitus (T2DM). From several pathological mechanisms involved in T2DM-DKD, we …
Nestin+ kidney resident mesenchymal stem cells for the treatment of acute kidney ischemia injury
MH Jiang, G Li, J Liu, L Liu, B Wu, W Huang, W He… - Biomaterials, 2015 - Elsevier
Renal resident mesenchymal stem cells (MSCs) are important regulators of kidney
homeostasis, repair or regeneration. However, natural distribution and the starting …
homeostasis, repair or regeneration. However, natural distribution and the starting …
[HTML][HTML] Mesenchymal stem cell therapy in acute kidney injury (AKI): review and perspectives
C Sávio-Silva, PE Soinski-Sousa… - Revista da Associação …, 2020 - SciELO Brasil
SUMMARY INTRODUCTION: Acute kidney injury (AKI) is highly prevalent today. It has a
multifactorial aetiology and affects people of all ages, genders and ethnicities. Its treatment …
multifactorial aetiology and affects people of all ages, genders and ethnicities. Its treatment …
DAB2IP regulates cancer stem cell phenotypes through modulating stem cell factor receptor and ZEB1
Cancer stem cell (CSC), the primary source of cancer-initiating population, is involved in
cancer recurrence and drug-resistant phenotypes. This study demonstrates that the loss of …
cancer recurrence and drug-resistant phenotypes. This study demonstrates that the loss of …