Objectives The continuing rise in infections caused by multidrug-resistant (MDR) bacteria is
one of the most serious public-health issues in society today. Colistin is a last-resort …

The worldwide spread of carbapenem-and polymyxin-resistant Enterobacterales represents
an urgent public-health threat. However, for most countries in the Americas, the available …

Objectives: The growing incidence of multidrug-resistant (MDR) bacteria is an inexorable
and fatal challenge in modern medicine. Colistin is a cationic polypeptide considered a “last …

The mcr-type gene encodes the main plasmid-mediated mechanism of colistin resistance
and has been reported in several bacterial species obtained from different sources …

In the last decade, polymyxins have been reintroduced in the therapeutic arsenal to treat
severe infections by carbapenem-resistant Enterobacterales. At that time, reports of …

Salmonella is a significant foodborne pathogen, the increased rate of detecting rate of
florfenicol-resistant Salmonella poses a serious threat to public health. This study used a …

Extended-spectrum β-lactamase (ESBL)-producing Escherichia coli (ESBL-EC) is regarded
as one of the most important priority pathogens within the One Health interface. However …

Objective To describe the molecular mechanisms of polymyxins resistance in five
Enterobacteriaceae clinical isolates from a tertiary hospital of Recife, Brazil. Methods The …

The incidence of infections caused by resistant Gram-negative pathogens has become a
critical factor in public health due to the limitation of therapeutic options for the control of …

Background The rapid and global spread of Escherichia coli carrying mcr-type genes at the
human-animal-environmental interface has become a serious global public health problem …