[HTML][HTML] More than addiction—the nucleus accumbens contribution to development of mental disorders and neurodegenerative diseases

M Bayassi-Jakowicka, G Lietzau, E Czuba… - International journal of …, 2022 - mdpi.com
Stress and negative emotions evoked by social relationships and working conditions,
frequently accompanied by the consumption of addictive substances, and metabolic and/or …

Structural and biochemical alterations in dendritic spines as key mechanisms for severe mental illnesses

S Reyes-Lizaola, U Luna-Zarate… - Progress in Neuro …, 2024 - Elsevier
Severe mental illnesses (SMI) collectively affect approximately 20% of the global population,
as estimated by the World Health Organization (WHO). Despite having diverse etiologies …

Treatment of cancer with antipsychotic medications: Pushing the boundaries of schizophrenia and cancer

JS Brown - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Over a century ago, the phenothiazine dye, methylene blue, was discovered to have both
antipsychotic and anti-cancer effects. In the 20th-century, the first phenothiazine …

Second-generation antipsychotic olanzapine attenuates behavioral and prefrontal cortex synaptic plasticity deficits in a neurodevelopmental schizophrenia-related rat …

DJ Apam-Castillejos, H Tendilla-Beltrán… - Journal of chemical …, 2022 - Elsevier
Second-generation antipsychotics are the drugs of choice for the treatment of
neurodevelopmental-related mental diseases such as schizophrenia. Despite the …

An Investigation of the Sodium Nitroprusside Effects on Serum Lipids in an Animal Model of Schizophrenia by the Magnetic Resonance Study

JGM Pontes, JVS Nani, BSB Correia… - ACS …, 2024 - ACS Publications
Schizophrenia (SCZ) is a multifactorial mental illness with limited knowledge concerning
pathogenesis, contributing to the lack of effective therapies. More recently, the use of a nitric …

Analysis of safe storage of network information data and financial risks under blockchain combined with edge computing

X Liang, W Ruan, Z Xu, J Liu - Journal of Global Information …, 2022 - igi-global.com
To discuss the control of financial risks (FRs) under blockchain (BC) and improve network
information security (NIS) and data security, edge computing (EC) combined with BC is …

Differential Effects of Neonatal Ventral Hippocampus Lesion on Behavior and Corticolimbic Plasticity in Wistar–Kyoto and Spontaneously Hypertensive Rats

H Tendilla-Beltrán, L Garcés-Ramírez… - Neurochemical …, 2024 - Springer
Dysfunction of the corticolimbic system, particularly at the dendritic spine level, is a
recognized core mechanism in neurodevelopmental disorders such as schizophrenia …

Losartan enhances cognitive and structural neuroplasticity impairments in spontaneously hypertensive rats

H Coatl-Cuaya, H Tendilla-Beltrán… - Journal of Chemical …, 2022 - Elsevier
Hypertension is a risk factor for vascular dementia, which is the second most prevalent type
of dementia, just behind Alzheimer's disease. This highlights the brain vulnerability due to …

Long non-coding RNAs in schizophrenia: genetic variations, treatment markers and potential targeted signaling pathways

T Cao, SY Zhang, Q Chen, CR Zeng, LW Wang… - Schizophrenia …, 2023 - Elsevier
Schizophrenia (SZ), a complex and debilitating spectrum of psychiatric disorders, is now
mainly attributed to multifactorial etiology that includes genetic and environmental factors …

Aripiprazole attenuates the medial prefrontal cortex morphological and biochemical alterations in rats with neonatal ventral hippocampus lesion

GD Flores-Gómez, DJ Apam-Castillejos… - Journal of Chemical …, 2023 - Elsevier
Schizophrenia is a neurodevelopmental disorder characterized by a loss of dendritic spines
in the medial prefrontal cortex (mPFC). Multiple subclinical and clinical studies have …