The mechanical phenotype of a cell determines its ability to deform under force and is
therefore relevant to cellular functions that require changes in cell shape, such as migration …

The plasma membrane separates the interior of cells from the outside environment. The
membrane tension, defined as the force per unit length acting on a cross-section of …

Malignant transformation and tumour progression are associated with cancer-cell softening.
Yet how the biomechanics of cancer cells affects T-cell-mediated cytotoxicity and thus the …

In response to different types and intensities of mechanical force, cells modulate their
physical properties and adapt their plasma membrane (PM). Caveolae are PM nano …

Malignancy is associated with changes in cell mechanics that contribute to extensive cell
deformation required for metastatic dissemination. We hypothesized that the cell-intrinsic …

The nanoscopic layer of water that directly hydrates biological membranes plays a critical
role in maintaining the cell structure, regulating biochemical processes, and managing …

Progress in the field of nanoparticles has enabled the rapid development of multiple
products and technologies; however, some nanoparticles can pose both a threat to the …

Cholesterol depletion by methyl-β-cyclodextrin (MβCD) remodels the plasma membrane's
mechanics in cells and its interactions with the underlying cytoskeleton, whereas in red …

The mechanical properties of living tissues have a significant impact on cell differentiation,
but remain unexplored in the context of myelin formation and repair. In the PNS, the …

Optical tweezers have become an important instrument in force measurements associated
with various physical, biological, and biophysical phenomena. Quantitative use of optical …