Regulated cell death pathways in kidney disease

AB Sanz, MD Sanchez-Niño, AM Ramos… - Nature Reviews …, 2023‏ - nature.com
Disorders of cell number that result from an imbalance between the death of parenchymal
cells and the proliferation or recruitment of maladaptive cells contributes to the pathogenesis …

Glomerulonephritis: immunopathogenesis and immunotherapy

HJ Anders, AR Kitching, N Leung… - Nature Reviews …, 2023‏ - nature.com
Abstract 'Glomerulonephritis'(GN) is a term used to describe a group of heterogeneous
immune-mediated disorders characterized by inflammation of the filtration units of the kidney …

Inaxaplin for Proteinuric Kidney Disease in Persons with Two APOL1 Variants

O Egbuna, B Zimmerman, G Manos… - … England Journal of …, 2023‏ - Mass Medical Soc
Background Persons with toxic gain-of-function variants in the gene encoding
apolipoprotein L1 (APOL1) are at greater risk for the development of rapidly progressive …

Genetics of chronic kidney disease

A Vivante - New England Journal of Medicine, 2024‏ - Mass Medical Soc
Key Points Genetics of Chronic Kidney Disease Genetic causes of chronic kidney disease
(CKD) are not uncommon. Patients with CKD should be referred for genetic consultation and …

The immunology of systemic lupus erythematosus

GC Tsokos - Nature Immunology, 2024‏ - nature.com
Understanding the pathogenesis and clinical manifestations of systemic lupus
erythematosus (SLE) has been a great challenge. Reductionist approaches to understand …

COVID-19-associated acute kidney injury: consensus report of the 25th Acute Disease Quality Initiative (ADQI) Workgroup

MK Nadim, LG Forni, RL Mehta, MJ Connor Jr… - Nature reviews …, 2020‏ - nature.com
Kidney involvement in patients with coronavirus disease 2019 (COVID-19) is common, and
can range from the presence of proteinuria and haematuria to acute kidney injury (AKI) …

[کتاب][B] Examining illiberal trends and anti-EU politics in east Central Europe from a domestic perspective: State of research and outline of the book

LH Anders, A Lorenz - 2021‏ - library.oapen.org
In East Central Europe (ECE), democracy and the rule of law are under siege, most notably
in Hungary and Poland and, to a lesser extent, also in the Czech Republic and Slovakia …

Genome-wide polygenic score to predict chronic kidney disease across ancestries

A Khan, MC Turchin, A Patki, V Srinivasasainagendra… - Nature medicine, 2022‏ - nature.com
Chronic kidney disease (CKD) is a common complex condition associated with high
morbidity and mortality. Polygenic prediction could enhance CKD screening and prevention; …

A brief history of human disease genetics

M Claussnitzer, JH Cho, R Collins, NJ Cox… - Nature, 2020‏ - nature.com
A primary goal of human genetics is to identify DNA sequence variants that influence
biomedical traits, particularly those related to the onset and progression of human disease …

Kidney biopsy findings in patients with COVID-19

S Kudose, I Batal, D Santoriello, K Xu… - Journal of the …, 2020‏ - journals.lww.com
Background Coronavirus disease 2019 (COVID-19) is thought to cause kidney injury by a
variety of mechanisms. To date, pathologic analyses have been limited to patient reports …