[HTML][HTML] The biphasic role of the infrapatellar fat pad in osteoarthritis

S Yue, G Zhai, S Zhao, X Liang, Y Liu, X Chen… - Biomedicine & …, 2024 - Elsevier
Osteoarthritis (OA) is a progressive degenerative disease resulting in joint deterioration. It is
a whole organ disease characterized by cartilage degeneration and varying degrees of …

Integrin signalling in joint development, homeostasis and osteoarthritis

MZ Miao, JS Lee, KM Yamada, RF Loeser - Nature Reviews …, 2024 - nature.com
Integrins are key regulators of cell–matrix interactions during joint development and joint
tissue homeostasis, as well as in the development of osteoarthritis (OA). The signalling …

Targeted macrophage CRISPR‐cas13 mRNA editing in immunotherapy for tendon injury

S Wang, Y ** an immune
microenvironment conducive to bone and cartilage growth is crucial for efficient tackling of …

[HTML][HTML] Lysosomal destabilization: A missing link between pathological calcification and osteoarthritis

T Ye, C Wang, J Yan, Z Qin, W Qin, Y Ma, Q Wan… - Bioactive Materials, 2024 - Elsevier
Calcification of cartilage by hydroxyapatite is a hallmark of osteoarthritis and its deposition
strongly correlates with the severity of osteoarthritis. However, no effective strategies are …