Oleuropein in olive and its pharmacological effects
SH Omar - Scientia pharmaceutica, 2010 - mdpi.com
Olive from Olea europaea is native to the Mediterranean region and, both the oil and the fruit
are some of the main components of the Mediterranean diet. The main active constituents of …
are some of the main components of the Mediterranean diet. The main active constituents of …
Research progress of polycyclic polyprenylated acylphloroglucinols
XW Yang, RB Grossman, G Xu - Chemical reviews, 2018 - ACS Publications
Polycyclic polyprenylated acylphloroglucinols (PPAPs) are a class of hybrid natural products
sharing the mevalonate/methylerythritol phosphate and polyketide biosynthetic pathways …
sharing the mevalonate/methylerythritol phosphate and polyketide biosynthetic pathways …
New aspects of natural products in drug discovery
KS Lam - Trends in microbiology, 2007 - cell.com
During the past 15 years, most large pharmaceutical companies have decreased the
screening of natural products for drug discovery in favor of synthetic compound libraries …
screening of natural products for drug discovery in favor of synthetic compound libraries …
Advances in structure elucidation of small molecules using mass spectrometry
The structural elucidation of small molecules using mass spectrometry plays an important
role in modern life sciences and bioanalytical approaches. This review covers different soft …
role in modern life sciences and bioanalytical approaches. This review covers different soft …
Quercetin and related polyphenols: new insights and implications for their bioactivity and bioavailability
K Kawabata, R Mukai, A Ishisaka - Food & function, 2015 - pubs.rsc.org
The physiological functions and bioavailability of flavonoids have been widely investigated
since their bioactivities were identified about 80 years ago. Quercetin is a typical flavonoid …
since their bioactivities were identified about 80 years ago. Quercetin is a typical flavonoid …
Dereplication strategies in natural product research: How many tools and methodologies behind the same concept?
The development of new drugs will certainly benefit from an ever improving knowledge of
the living beings chemistry. However, identification of drugable molecules within the …
the living beings chemistry. However, identification of drugable molecules within the …
High resolution NMR spectroscopy as a structural and analytical tool for unsaturated lipids in solution
Mono-and polyunsaturated lipids are widely distributed in Nature, and are structurally and
functionally a diverse class of molecules with a variety of physicochemical, biological …
functionally a diverse class of molecules with a variety of physicochemical, biological …
Dereplication: racing to speed up the natural products discovery process
Covering: 1993–2014 (July) To alleviate the dereplication holdup, which is a major
bottleneck in natural products discovery, scientists have been conducting their research …
bottleneck in natural products discovery, scientists have been conducting their research …
Single-cell RNA sequencing facilitates the elucidation of the complete biosynthesis of the antidepressant hyperforin in St. John's wort
Hyperforin is the compound responsible for the effectiveness of St. John's wort (Hypericum
perforatum) as an antidepressant, but its complete biosynthetic pathway remains unknown …
perforatum) as an antidepressant, but its complete biosynthetic pathway remains unknown …
Identification and Quantification of Flavonoids and Phenolic Acids in Burr Parsley (Caucalis platycarpos L.), Using High-Performance Liquid Chromatography with …
A sensitive method coupling high-performance liquid chromatography (HPLC) with diode-
array detector (DAD) and electrospray ionization mass spectrometry (MS) was optimized for …
array detector (DAD) and electrospray ionization mass spectrometry (MS) was optimized for …