Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function
MT Abreu - Nature reviews immunology, 2010 - nature.com
A single layer of epithelial cells lines the small and large intestines and functions as a barrier
between commensal bacteria and the rest of the body. Ligation of Toll-like receptors (TLRs) …
between commensal bacteria and the rest of the body. Ligation of Toll-like receptors (TLRs) …
How the intricate interaction among toll‐like receptors, microbiota, and intestinal immunity can influence gastrointestinal pathology
The gut is able to maintain tolerance to microbial and food antigens. The intestine minimizes
the number of harmful bacteria by sha** the microbiota through a symbiotic relationship …
the number of harmful bacteria by sha** the microbiota through a symbiotic relationship …
TLR signaling in the gut in health and disease
MT Abreu, M Fukata, M Arditi - The Journal of Immunology, 2005 - journals.aai.org
The human intestine has evolved in the presence of diverse enteric microflora. TLRs convert
the recognition of pathogen-associated molecules in the gut into signals for anti-microbial …
the recognition of pathogen-associated molecules in the gut into signals for anti-microbial …
Toll-like receptors in inflammatory bowel diseases: a decade later
E Cario - Inflammatory bowel diseases, 2010 - academic.oup.com
Differential alteration of Toll-like receptor (TLR) expression in inflammatory bowel disease
(IBD) was first described 10 years ago. Since then, studies from many groups have led to the …
(IBD) was first described 10 years ago. Since then, studies from many groups have led to the …
Toll-like receptors in ischemia-reperfusion injury
Abstract Ischemia-reperfusion (I/R) injuries are implicated in a large array of pathological
conditions such as myocardial infarction, cerebral stroke, and hepatic, renal, and intestinal …
conditions such as myocardial infarction, cerebral stroke, and hepatic, renal, and intestinal …
Bacterial interactions with cells of the intestinal mucosa: Toll-like receptors and NOD2
E Cario - Gut, 2005 - gut.bmj.com
Toll-like receptors (TLR) and NOD2 are emerging as key mediators of innate host defence in
the intestinal mucosa, crucially involved in maintaining mucosal as well as commensal …
the intestinal mucosa, crucially involved in maintaining mucosal as well as commensal …
Regulation of intestinal immune responses through TLR activation: implications for pro-and prebiotics
The intestinal mucosa is constantly facing a high load of antigens including bacterial
antigens derived from the microbiota and food. Despite this, the immune cells present in the …
antigens derived from the microbiota and food. Despite this, the immune cells present in the …
Toll-like receptors in inflammation, infection and cancer
Members of the Toll-like receptor (TLR) family play key roles in both innate and adaptive
immune responses. TLR proteins enable host to recognize a large number of pathogen …
immune responses. TLR proteins enable host to recognize a large number of pathogen …
LPS induces hyper‐permeability of intestinal epithelial cells
Necrotizing Enterocolitis (NEC) is a severe inflammatory disorder leading to high morbidity
and mortality rates. A growing body of evidence demonstrate the key role of the Toll like …
and mortality rates. A growing body of evidence demonstrate the key role of the Toll like …
[HTML][HTML] IL-18 in autoimmunity
D Boraschi, CA Dinarello - European cytokine network, 2006 - jle.com
5 Schmitz J, Owyang A, Oldham E, Song Y, Murphy E, McClanaham TK, Zurawski G,
Moshrefi M, Qin J, Li X, Gorman DM, Bazan JF, Kastelein RA. IL-33, an interleukin-1-like …
Moshrefi M, Qin J, Li X, Gorman DM, Bazan JF, Kastelein RA. IL-33, an interleukin-1-like …