The role of senescent T cells in immunopathology
LP Covre, RPH De Maeyer, DCO Gomes… - Aging cell, 2020 - Wiley Online Library
The development of senescence in tissues of different organs and in the immune system are
usually investigated independently of each other although during ageing, senescence in …
usually investigated independently of each other although during ageing, senescence in …
Ageing with HIV: Challenges and biomarkers
B Rodes, J Cadinanos, A Esteban-Cantos… - …, 2022 - thelancet.com
The antiretroviral treatment (ART) developed to control HIV infection led to a revolution in the
prognosis of people living with HIV (PLWH). PLWH underwent from suffering severe disease …
prognosis of people living with HIV (PLWH). PLWH underwent from suffering severe disease …
Sicilian semi-and supercentenarians: Identification of age-related T-cell immunophenotype to define longevity trait
ME Ligotti, G Accardi, A Aiello, S Aprile… - Clinical and …, 2023 - academic.oup.com
The immunophenotype of oldest centenarians, ie semi-and supercentenarians, could
provide important information about their ability to adapt to factors associated with immune …
provide important information about their ability to adapt to factors associated with immune …
Long COVID as a disease of accelerated biological aging: An opportunity to translate geroscience interventions
It has been four years since long COVID—the protracted consequences that survivors of
COVID-19 face—was first described. Yet, this entity continues to devastate the quality of life …
COVID-19 face—was first described. Yet, this entity continues to devastate the quality of life …
3D printed ocusert laden with ultra-fluidic glycerosomes of ganciclovir for the management of ocular cytomegalovirus retinitis
Cytomegalovirus (CMV) retinitis is a vision-threatening disease that principally afflicts
immunosuppressed patients. For the management of the disease, Ganciclovir (GCV) is …
immunosuppressed patients. For the management of the disease, Ganciclovir (GCV) is …
Cytomegalovirus and Epstein–Barr virus co-infected young and middle-aged adults can have an aging-related T-cell phenotype
MI Hofstee, A Cevirgel, ML de Zeeuw-Brouwer… - Scientific Reports, 2023 - nature.com
Cytomegalovirus (CMV) is known to alter circulating effector memory or re-expressing
CD45RA+ (TemRA) T-cell numbers, but whether Epstein–Barr virus (EBV) does the same or …
CD45RA+ (TemRA) T-cell numbers, but whether Epstein–Barr virus (EBV) does the same or …
[PDF][PDF] Interactomics: dozens of viruses, co-evolving with humans, including the influenza A virus, may actively distort human aging
J Teulière, C Bernard, H Bonnefous… - Molecular biology …, 2023 - academic.oup.com
Some viruses (eg, human immunodeficiency virus 1 and severe acute respiratory syndrome
coronavirus 2) have been experimentally proposed to accelerate features of human aging …
coronavirus 2) have been experimentally proposed to accelerate features of human aging …
Advanced biological age is associated with improved antibody responses in older high-dose influenza vaccine recipients over four consecutive seasons
Background Biological aging represents a loss of integrity and functionality of physiological
systems over time. While associated with an enhanced risk of adverse outcomes such as …
systems over time. While associated with an enhanced risk of adverse outcomes such as …
Understanding the interaction between cytomegalovirus and tuberculosis in children: the way forward
Over 1 million children develop tuberculosis (TB) each year, with a quarter dying. Multiple
factors impact the risk of a child being exposed to Mycobacterium tuberculosis (Mtb), the risk …
factors impact the risk of a child being exposed to Mycobacterium tuberculosis (Mtb), the risk …
Immune dysfunction from radiation exposure
BA Hollingsworth, JT Aldrich, CM Case Jr… - Radiation …, 2023 - meridian.allenpress.com
The hematopoietic system is highly sensitive to ionizing radiation. Damage to the immune
system may result in opportunistic infections and hemorrhage, which could lead to mortality …
system may result in opportunistic infections and hemorrhage, which could lead to mortality …